The　minimum　hot　and　cold　utilities　of　heat　exchanger　networks　can　be　obtained　based　on　the　principle　of　pinch　theory.　Moreover,　reasonable　process　changes　can　further　reduce　hot　and　cold　utilities.　Meanwhile,　adding　heat　pumps　correctly　in　a　heat　exchanger　network　can　reuse　the　waste　heat　below　the　pinch,　which　reduces　both　hot　and　cold　utilities　and　enhances　energy　utilization.　The　influence　of　process　changes　on　hot　and　cold　utilities　of　heat　exchanger　networks　with　heat　pumps　was　analyzed　by　a　graphical　method　based　on　the　pinch　technology.　The　results　show　that　a　process　change　that　originally　cannot　reduce　hot　and　cold　utilities　can　be　transformed　into　one　that　can　save　utilities　with　the　help　of　heat　pumps.　Therefore,　for　heat　exchanger　networks　with　heat　pumps,　whether　a　process　change　is　profitable　also　depends　on　the　influence　of　heat　pumps.　This　work　extends　the　research　scope　of　process　change　and　the　acquired　results　provide　theoretical　criteria　for　reasonable　process　changes.　©　2016,　Zhejiang　University.　All　right　reserved.