Bacteria-infected　wounds　and　antibiotics　abuse　have　become　significant　burdens　to　patients　and　medical　systems.　Thus,　designing　a　non-antibiotic-dependent　multifunctional　wound　dressing　for　treating　bacteria-infected　wounds　is　urgently　desired.　Herein,　a　series　of　conductive　self-healing　and　adhesive　nanocomposite　hydrogels　with　a　remarkable　photothermal　antibacterial　property　based　on　N-carboxyethyl　chitosan　(CEC)　and　benzaldehyde-terminated　Pluronic　F127/carbon　nanotubes　(PF127/CNT)　were　developed,　and　their　great　potential　as　agents　for　photothermal　therapy　(PTT)　of　infected　wounds　was　demonstrated　in　vivo.　The　hydrogels　exhibited　a　suitable　gelation　time,　stable　mechanical　properties,　hemostatic　properties,　high　water　absorbency,　and　good　biodegradability.　After　loading　the　antibiotic　moxifloxacin　hydrochloride,　the　hydrogels　showed　a　pH-responsive　release　profile　and　good　antibacterial　activity.　The　tissue　adhesive　property　of　the　hydrogels　allowed　them　to　have　a　good　hemostatic　effect　in　a　mouse　liver　trauma　model,　mouse　liver　incision　model,　and　mouse　tale　amputation　model.　The　addition　of　CNTs　endowed　the　hydrogel　with　in　vitro/in　vivo　photothermal　antimicrobial　activity　and　good　conductivity.　An　in　vivo　experiment　in　a　mouse　full-thickness　skin　wound-infected　model　indicated　that　the　hydrogels　had　an　excellent　treatment　effect　leading　to　significantly　enhanced　wound　closure　healing,　collagen　deposition,　and　angiogenesis.　In　summary,　these　conductive　photothermal　self-healing　nanocomposite　hydrogels　as　multifunctional　wound　dressing　exhibit　great　potential　for　the　treatment　of　infected　wounds.　©　2020　Elsevier　B.V.