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Computational analysis of knee joint stability following total knee arthroplasty. PubMed SCIE
期刊论文 | 2019 , 86 , 17-26 | Journal of biomechanics
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Abstract :

The overall objective of this study was to introduce knee joint power as a potential measure to investigate knee joint stability following total knee arthroplasty (TKA). Specific aims were to investigate whether weakened knee joint stabilizers cause abnormal kinematics and how it influences the knee joint kinetic (i.e., power) in response to perturbation. Patient-specific musculoskeletal models were simulated with experimental gait data from six TKA patients (baseline models). Muscle strength and ligament force parameter were reduced by up to 30% to simulate weak knee joint stabilizers (weak models). Two different muscle recruitment criteria were tested to examine whether altered muscle recruitment pattern can mask the influence of weakened stabilizers on the knee joint kinematics and kinetics. Level-walking knee joint kinematics and kinetics were calculated though force-dependent kinematic and inverse dynamic analyses. Bode analysis was then recruited to estimate the knee joint power in response to a simulated perturbation. Weak models resulted in larger anterior-posterior (A-P) displacement and internal-external (I-E) rotation compared to baseline (I-E: 18.4 ± 8.5 vs. 11.6 ± 5.7 (deg), A-P: 9.7 ± 5.6 vs. 5.5 ± 4.1 (mm)). Changes in muscle recruitment criterion however altered the results such that A-P and I-E were not notably different from baseline models. In response to the simulated perturbation, weak models versus baseline models generated a delayed power response with unbounded magnitudes. Perturbed power behavior of the knee remained unaltered regardless of the muscle recruitment criteria. In conclusion, impairment at the knee joint stabilizers may or may not lead to excessive joint motions but it notably affects the knee joint power in response to a perturbation. Whether perturbed knee joint power is associated with the patient-reported outcome requires further investigation.

Keyword :

Instability Knee kinematics Bode analysis Total knee arthroplasty Gait

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GB/T 7714 Ardestani Marzieh M , ZhenXian Chen , Noori Hessam et al. Computational analysis of knee joint stability following total knee arthroplasty. [J]. | Journal of biomechanics , 2019 , 86 : 17-26 .
MLA Ardestani Marzieh M et al. "Computational analysis of knee joint stability following total knee arthroplasty." . | Journal of biomechanics 86 (2019) : 17-26 .
APA Ardestani Marzieh M , ZhenXian Chen , Noori Hessam , Moazen Mehran , Jin Zhongmin . Computational analysis of knee joint stability following total knee arthroplasty. . | Journal of biomechanics , 2019 , 86 , 17-26 .
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Biphasic osteochondral scaffold fabrication using multi-material mask projection stereolithography EI Scopus SCIE
期刊论文 | 2019 , 25 (2) , 277-288 | Rapid Prototyping Journal
WoS CC Cited Count: 2 SCOPUS Cited Count: 1
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Abstract :

Purpose: This study aims to develop a multi-material stereolithography (MMSL) technique to directly fabricate a biphasic osteochondral scaffold. Design/methodology/approach: A bespoke prototype MMSL system was developed based on a bottom-up mask projection approach. The system was controlled by a multi-material fabrication algorithm with minimum number of switching cycles during fabrication. A variable-power light source was used to fabricate materials with significantly different curing characteristics. The light-curable poly(ethylene glycol) diacrylate (PEGDA) hydrogel and beta-tricalcium phosphate (β-TCP) ceramic suspension were used for fabricating the biphasic osteochondral scaffold. Findings: The bonding strength of the multi-material interface is shown to be mainly affected by the type of photopolymer, rather than the switching of the materials in MMSL. Lighting power densities of 2.64 and 14.98 mW/cm2 were used for curing the PEGDA hydrogel and the ß-TCP ceramic suspension, respectively. A biphasic osteochondral scaffold with complex interface was successfully fabricated. Originality/value: This study proposes a potential technical method (MMSL) for manufacturing a complex biphasic osteochondral scaffold composing a PEGDA hydrogel/ß-TCP ceramic composite in a time-efficient and precise manner. The designed bone-cartilage scaffold interface and the surface of the cartilage scaffold can be precisely manufactured. © 2018, Emerald Publishing Limited.

Keyword :

Ceramic suspensions Mask projection Multi materials Osteochondral Variable power

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GB/T 7714 Wu, Xiangquan , Lian, Qin , Li, Dichen et al. Biphasic osteochondral scaffold fabrication using multi-material mask projection stereolithography [J]. | Rapid Prototyping Journal , 2019 , 25 (2) : 277-288 .
MLA Wu, Xiangquan et al. "Biphasic osteochondral scaffold fabrication using multi-material mask projection stereolithography" . | Rapid Prototyping Journal 25 . 2 (2019) : 277-288 .
APA Wu, Xiangquan , Lian, Qin , Li, Dichen , Jin, Zhongmin . Biphasic osteochondral scaffold fabrication using multi-material mask projection stereolithography . | Rapid Prototyping Journal , 2019 , 25 (2) , 277-288 .
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多材料面曝光增材制造方法与加工工艺研究
期刊论文 | 2018 , (1) , 47-50,60 | 电加工与模具
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Abstract :

零件的多材料组成可改变其机械性能,并增加其他附属功能.通过搭建一种分区旋转槽多材料面曝光增材制造系统,验证了多材料光固化成形工艺,完成了含有两种树脂材料的复杂结构零件的加工.分析了零件的加工质量和加工精度,并进行了多材料界面结合的抗拉和抗剪性能测试.结果表明:所加工的多材料界面在拉应力和剪应力的作用下结合良好.

Keyword :

面曝光 多材料 旋转槽 增材制造

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GB/T 7714 武向权 , 连芩 , 何晓宁 et al. 多材料面曝光增材制造方法与加工工艺研究 [J]. | 电加工与模具 , 2018 , (1) : 47-50,60 .
MLA 武向权 et al. "多材料面曝光增材制造方法与加工工艺研究" . | 电加工与模具 1 (2018) : 47-50,60 .
APA 武向权 , 连芩 , 何晓宁 , 孟佳丽 , 李涤尘 , 靳忠民 . 多材料面曝光增材制造方法与加工工艺研究 . | 电加工与模具 , 2018 , (1) , 47-50,60 .
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Study on biocompatibility, tribological property and wear debris characterization of ultra-low-wear polyethylene as artificial joint materials EI SCIE PubMed Scopus
期刊论文 | 2018 , 82 , 87-94 | JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
WoS CC Cited Count: 2 SCOPUS Cited Count: 2
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Abstract :

Ultra-low-wear polyethylene (ULWPE) is a new type polyethylene made by experts who are from China petrochemical research institute, which is easy to process and implant. Preliminary test showed it was more resistant to wear than that of Ultra-high-molecular weight polyethylene (UHMWPE). The purpose of the research is to study biocompatibility, bio-tribological properties and debris characterization of ULWPE. Cytotoxicity test, hemolysis test, acute/chronic toxicity and muscular implantation test were conducted according to national standard GB/T-16886/ISO-10993 for evaluation requirements of medical surgical implants. We obtained that this novel material had good biocompatibility and biological safety. The wear performance of ULWPE and UHMWPE was evaluated in a pin-on-disc (POD) wear tester within two million cycles and a knee wear simulator within six million cycles. We found that the ULWPE was higher abrasion resistance than the UHMWPE, the wear rate of ULWPE by POD test and knee wear simulator was 0.4 mg/10(6)cycles and (16.9 +/- 1.8)mg/10(6)cycles respectively, while that of UHMWPE was 1.8 mg/10(6)cycles and (24.6 +/- 2.4)mg/10(6)cycles. The morphology of wear debris is also an important factor to evaluate artificial joint materials, this study showed that the ULWPE wear debris gotten from the simulator had various different shapes, including spherical, block, tear, etc. The morphology of worn surface and wear debris analysis showed that wear mechanisms of ULWPE were adhesion wear, abrasive wear and fatigue wear and other wear forms, which were consistent with that of UHMWPE. Thus we conclude that ULWPE is expected to be a lifetime implantation of artificial joint.

Keyword :

Wear debris Biocompatibility Bio-tribology Ultra-low-wear polyethylene (ULWPE) Artificial joints

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GB/T 7714 Bian, Yan-Yan , Zhou, Lei , Zhou, Gang et al. Study on biocompatibility, tribological property and wear debris characterization of ultra-low-wear polyethylene as artificial joint materials [J]. | JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS , 2018 , 82 : 87-94 .
MLA Bian, Yan-Yan et al. "Study on biocompatibility, tribological property and wear debris characterization of ultra-low-wear polyethylene as artificial joint materials" . | JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS 82 (2018) : 87-94 .
APA Bian, Yan-Yan , Zhou, Lei , Zhou, Gang , Jin, Zhong-Min , Xin, Shi-Xuan , Hua, Zi-Kai et al. Study on biocompatibility, tribological property and wear debris characterization of ultra-low-wear polyethylene as artificial joint materials . | JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS , 2018 , 82 , 87-94 .
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Laser Metal Direct Forming of the Customized Titanium Implants EI SCIE Scopus CSCD PKU
期刊论文 | 2017 , 46 (7) , 1924-1928 | RARE METAL MATERIALS AND ENGINEERING | IF: 0.29
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Laser metal direct forming technology was applied to manufacture customized titanium implants, and then titanium implants can be directly formed according to their CAD models. This method possesses a short manufacturing cycle. Additionally, the customized titanium implants manufactured in this method have good mechanical properties. The influences of curvature effect and inclination angle on the geometric precision of laser metal direct forming parts were studied for the establishment of the model design criteria. Therefore, the formed titanium implant could achieve high precision. Both mechanical properties and chemical composition of the manufactured customized titanium implants comply with relevant national and pharmaceutical industry standards. Two cases of customized titanium implants manufactured by laser metal direct forming have been successfully applied in clinical and have achieved good results.

Keyword :

implant customized laser metal direct forming

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GB/T 7714 Qin Mian , Liu Yaxiong , Wang Ling et al. Laser Metal Direct Forming of the Customized Titanium Implants [J]. | RARE METAL MATERIALS AND ENGINEERING , 2017 , 46 (7) : 1924-1928 .
MLA Qin Mian et al. "Laser Metal Direct Forming of the Customized Titanium Implants" . | RARE METAL MATERIALS AND ENGINEERING 46 . 7 (2017) : 1924-1928 .
APA Qin Mian , Liu Yaxiong , Wang Ling , Li Dichen , Jin Zhongmin , Liu Yanpu et al. Laser Metal Direct Forming of the Customized Titanium Implants . | RARE METAL MATERIALS AND ENGINEERING , 2017 , 46 (7) , 1924-1928 .
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双投影光固化成型方法研究 CSCD PKU
期刊论文 | 2017 , (2) , 149-154 | 西安交通大学学报
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Keyword :

快速成型 光固化成型 掩膜投影 微结构

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GB/T 7714 陈冬 , 王亚宁 , 刘亚雄 et al. 双投影光固化成型方法研究 [J]. | 西安交通大学学报 , 2017 , (2) : 149-154 .
MLA 陈冬 et al. "双投影光固化成型方法研究" . | 西安交通大学学报 2 (2017) : 149-154 .
APA 陈冬 , 王亚宁 , 刘亚雄 , 贺健康 , 王玲 , 连芩 et al. 双投影光固化成型方法研究 . | 西安交通大学学报 , 2017 , (2) , 149-154 .
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THE EFFECT OF ASPHERICITY OF ACETABULAR BEARING SURFACE ON CONTACT MECHANICS OF UHMWPE TOTAL HIP IMPLANTS BY FINITE ELEMENT ANALYSIS EI SCIE Scopus
期刊论文 | 2017 , 17 (1) , 14 | JOURNAL OF MECHANICS IN MEDICINE AND BIOLOGY | IF: 0.875
WoS CC Cited Count: 1 SCOPUS Cited Count: 1
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Abstract :

Asphericity and out-of-roundness are generally used to evaluate the manufacturing quality of ultra-high molecular weight polyethylene (UHMWPE) cup inner surfaces, which can potentially affect initial clinical wear and contribute to osteolysis of total hip arthroplasty. This study measured the location and magnitude of asphericity and the out-of-roundness value for four UHMWPE cups in a single set, and then investigated the effects of the asphericity on the contact mechanics of UHMWPE cups. A co-ordinate measuring machine (CMM) was used for the surface measurement and finite element analysis (FEA) was adopted for contact mechanics study. The results demonstrated that the asphericity varied between cups with the maximum value as 0.088 +/- 0.004 mm. Although such a value met the ISO specification, large difference of volume appeared for the asphericity above 0.060 mm. Actual surface profile accounting for the asphericity was found to affect the value of contact pressure and contact area by around 12%. The inferior asphericity resulted in a nonsmoothly distributed contact pressure, which had a negative effect on the contact mechanics of UHMWPE cups and the edge loading was predicted to occur for the sample with a large asphericity. In conclusion, the asphericity of UHMWPE cup could affect the contact mechanics of the articular bearings and may subsequently contribute to initial wear during bedding-in phase.

Keyword :

Total hip arthroplasty contact mechanics asphericity finite element analysis edge loading

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GB/T 7714 Zhang, Xuan , Wang, Ling , Peng, Xifeng et al. THE EFFECT OF ASPHERICITY OF ACETABULAR BEARING SURFACE ON CONTACT MECHANICS OF UHMWPE TOTAL HIP IMPLANTS BY FINITE ELEMENT ANALYSIS [J]. | JOURNAL OF MECHANICS IN MEDICINE AND BIOLOGY , 2017 , 17 (1) : 14 .
MLA Zhang, Xuan et al. "THE EFFECT OF ASPHERICITY OF ACETABULAR BEARING SURFACE ON CONTACT MECHANICS OF UHMWPE TOTAL HIP IMPLANTS BY FINITE ELEMENT ANALYSIS" . | JOURNAL OF MECHANICS IN MEDICINE AND BIOLOGY 17 . 1 (2017) : 14 .
APA Zhang, Xuan , Wang, Ling , Peng, Xifeng , Li, Dichen , He, Jiankang , Liu, Yaxiong et al. THE EFFECT OF ASPHERICITY OF ACETABULAR BEARING SURFACE ON CONTACT MECHANICS OF UHMWPE TOTAL HIP IMPLANTS BY FINITE ELEMENT ANALYSIS . | JOURNAL OF MECHANICS IN MEDICINE AND BIOLOGY , 2017 , 17 (1) , 14 .
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Mapping porous microstructures to yield desired mechanical properties for application in 3D printed bone scaffolds and orthopaedic implants EI SCIE Scopus
期刊论文 | 2017 , 133 , 62-68 | MATERIALS & DESIGN | IF: 4.525
WoS CC Cited Count: 24 SCOPUS Cited Count: 26
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Porous design of orthopaedic implants affords the advantages of minimizing stress shielding and improving the osseointegration and long-termstability. However, the marked error in the manufactured porous structure relative to the designed model yields limited application of the porous design. This study aimed to develop a methodology to derive the relationship between the porosity, the structural characteristic parameters and the mechanical properties of a typical structural unit, to lay the foundation of a porous structural design for 3D-printed implants with gradient modulus. Mathematical expressions related to porosity were determined based on various parametrical characteristics of porous units; the effective modulus of such a porous structure was studied under variable axial loading by using finite element analysis to gain insight into the anisotropic properties of the porous structure, and to evaluate the effects of parametrical variation on the aforementioned properties. For validation purposes, samples were manufactured via selective laser melting (SLM) 3D printing technology and mechanically tested. Results indicated that porous design can reduce the effective modulus of implants by 75-80%. A general methodology was developed for evaluating BCC structural units to determine design parameter correlations, the porosity and the effective modulus of the structure. (C) 2017 Published by Elsevier Ltd.

Keyword :

Mechanical property Orthopaedic implant 3D Printing Porous metal

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GB/T 7714 Wang, Ling , Kang, Jianfeng , Sun, Changning et al. Mapping porous microstructures to yield desired mechanical properties for application in 3D printed bone scaffolds and orthopaedic implants [J]. | MATERIALS & DESIGN , 2017 , 133 : 62-68 .
MLA Wang, Ling et al. "Mapping porous microstructures to yield desired mechanical properties for application in 3D printed bone scaffolds and orthopaedic implants" . | MATERIALS & DESIGN 133 (2017) : 62-68 .
APA Wang, Ling , Kang, Jianfeng , Sun, Changning , Li, Dichen , Cao, Yi , Jin, Zhongmin . Mapping porous microstructures to yield desired mechanical properties for application in 3D printed bone scaffolds and orthopaedic implants . | MATERIALS & DESIGN , 2017 , 133 , 62-68 .
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The effect of collagen fibril orientation on the biphasic mechanics of articular cartilage EI SCIE PubMed Scopus
期刊论文 | 2017 , 65 , 439-453 | JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS | IF: 3.239
WoS CC Cited Count: 12 SCOPUS Cited Count: 14
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The highly inhomogeneous distribution of collagen fibrils may have important effects on the biphasic mechanics of articular cartilage. However, the effect of the inhomogeneity of collagen fibrils has mainly been investigated using simplified three-layered models, which may have underestimated the effect of collagen fibrils by neglecting their realistic orientation. The aim of this study was to investigate the effect of the realistic orientation of collagen fibrils on the biphasic mechanics of articular cartilage. Five biphasic material models, each of which included a different level of complexity of fibril reinforcement, were solved using two different finite element software packages (Abaqus and FEBio). Model I considered the realistic orientation of fibrils, which was derived from diffusion tensor magnetic resonance images. The simplified three-layered orientation was used for Model 2. Models 3-5 were three control models. The realistic collagen orientations obtained in this study were consistent with the literature. Results from the two finite element implementations were in agreement for each of the conditions modelled. The comparison between the control models confirmed some functions of collagen fibrils. The comparison between Models 1 and 2 showed that the widely-used three-layered inhomogeneous model can produce similar fluid load support to the model including the realistic fibril orientation; however, an accurate prediction of the other mechanical parameters requires the inclusion of the realistic orientation of collagen fibrils. (C) 2016 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY license.

Keyword :

Biomechanics Fibril-reinforced biphasic model DT-MRI Articular cartilage Collagen fibril

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GB/T 7714 Meng, Qingen , An, Shuqiang , Damion, Robin A. et al. The effect of collagen fibril orientation on the biphasic mechanics of articular cartilage [J]. | JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS , 2017 , 65 : 439-453 .
MLA Meng, Qingen et al. "The effect of collagen fibril orientation on the biphasic mechanics of articular cartilage" . | JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS 65 (2017) : 439-453 .
APA Meng, Qingen , An, Shuqiang , Damion, Robin A. , Jin, Zhongmin , Wilcox, Ruth , Fisher, John et al. The effect of collagen fibril orientation on the biphasic mechanics of articular cartilage . | JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS , 2017 , 65 , 439-453 .
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Load application for the contact mechanics analysis and wear prediction of total knee replacement EI SCIE PubMed Scopus
期刊论文 | 2017 , 231 (5) , 444-454 | PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE | IF: 1.124
WoS CC Cited Count: 1
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Tibiofemoral contact forces in total knee replacement have been measured at the medial and lateral sites respectively using an instrumented prosthesis, and predicted from musculoskeletal multibody dynamics models with a reasonable accuracy. However, it is uncommon that the medial and lateral forces are applied separately to replace a total axial load according to the ISO standard in the majority of current finite element analyses. In this study, we quantified the different effects of applying the medial and lateral loads separately versus the traditional total axial load application on contact mechanics and wear prediction of a patient-specific knee prosthesis. The load application position played an important role under the medial-lateral load application. The loading set which produced the closest load distribution to the multibody dynamics model was used to predict the contact mechanics and wear for the prosthesis and compared with the total axial load application. The medial-lateral load distribution using the present method was found to be closer to the multibody dynamics prediction than the traditional total axial load application, and the maximum contact pressure and contact area were consistent with the corresponding load variation. The predicted total volumetric wear rate and area were similar between the two load applications. However, the split of the predicted wear volumes on the medial and the lateral sides was different. The lateral volumetric wear rate was 31.46% smaller than the medial from the traditional load application prediction, while from the medial-lateral load application, the lateral side was only 11.8% smaller than the medial. The medial-lateral load application could provide a new and more accurate method of load application for patient-specific preclinical contact mechanics and wear prediction of knee implants.

Keyword :

Axial load application finite element contact mechanics total knee replacement wear prediction

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GB/T 7714 Zhang, Jing , Chen, Zhenxian , Wang, Ling et al. Load application for the contact mechanics analysis and wear prediction of total knee replacement [J]. | PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE , 2017 , 231 (5) : 444-454 .
MLA Zhang, Jing et al. "Load application for the contact mechanics analysis and wear prediction of total knee replacement" . | PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE 231 . 5 (2017) : 444-454 .
APA Zhang, Jing , Chen, Zhenxian , Wang, Ling , Li, Dichen , Jin, Zhongmin . Load application for the contact mechanics analysis and wear prediction of total knee replacement . | PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE , 2017 , 231 (5) , 444-454 .
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