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Identifying suspicious groups of affiliated-transaction-based tax evasion in big data EI Scopus SSCI SCIE
期刊论文 | 2019 , 477 , 508-532 | Information Sciences
WoS CC Cited Count: 2 SCOPUS Cited Count: 2
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Abstract :

© 2018 Elsevier Inc. Affiliated-transaction-based tax evasion (ATTE) is a new strategy in tax evasion that is carried out via legal-like transactions between a group of companies that have heterogeneous, complex and covert interactive relationships to evade taxes. Existing studies cannot effectively detect ATTE behaviors since (i) they perform well only for determining the abnormal financial status of individuals and ineffectively address the interactive relationships among companies, (ii) they aim at detecting ATTE from the perspective of structural characteristics, which leads to a poor false-positive rate, and (iii) few of them perform well in most sectors of companies. Effectively detecting suspicious groups according to both structural characteristics of ATTE groups and business characteristics of ATTE means (BC-ATTEM) remains an open issue. In this paper, we propose an affiliated-parties interest-related network (APIRN) for modeling affiliated parties, interest-related relationships, and their properties for identifying ATTE. Then, we identify the behavioral patterns of ATTE via topological pattern abstraction from APIRN and theoretical inference of BC-ATTEM. Based on the above, we further propose a hybrid method, namely, 3TI, for identifying ATTE suspicious groups via three steps: tax rate differential detection, topological pattern matching and tax burden abnormality identification. Experimental tests that are based on two years of real-world tax data from a province in China demonstrate that 3TI can identify ATTE suspicious groups with higher accuracy and better generality than existing works. Moreover, we identify various interesting implications and provide useful guidance for ATTE inspection based on an analysis of our experimental results.

Keyword :

Affiliated transaction Big data Graph mining Tax evasion

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GB/T 7714 Ruan, Jianfei , Yan, Zheng , Dong, Bo et al. Identifying suspicious groups of affiliated-transaction-based tax evasion in big data [J]. | Information Sciences , 2019 , 477 : 508-532 .
MLA Ruan, Jianfei et al. "Identifying suspicious groups of affiliated-transaction-based tax evasion in big data" . | Information Sciences 477 (2019) : 508-532 .
APA Ruan, Jianfei , Yan, Zheng , Dong, Bo , Zheng, Qinghua , Qian, Buyue . Identifying suspicious groups of affiliated-transaction-based tax evasion in big data . | Information Sciences , 2019 , 477 , 508-532 .
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The inhibitor of apoptosis protein livin is upregulated in psoriasis vulgaris SCIE PubMed Scopus
期刊论文 | 2018 , 32 (6) , E245-E247 | JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
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GB/T 7714 Wang, H. , Ran, L. , Hui, K. et al. The inhibitor of apoptosis protein livin is upregulated in psoriasis vulgaris [J]. | JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY , 2018 , 32 (6) : E245-E247 .
MLA Wang, H. et al. "The inhibitor of apoptosis protein livin is upregulated in psoriasis vulgaris" . | JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY 32 . 6 (2018) : E245-E247 .
APA Wang, H. , Ran, L. , Hui, K. , Pei, X. , Wang, X. , Zheng, Y. . The inhibitor of apoptosis protein livin is upregulated in psoriasis vulgaris . | JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY , 2018 , 32 (6) , E245-E247 .
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GRIM-19在Bowen病和皮肤鳞状细胞癌组织中的表达
期刊论文 | 2018 , (6) , 936-938 | 现代肿瘤医学
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目的:通过研究GRIM-19在Bowen病和皮肤鳞癌皮损中的表达水平,来探讨GRIM-19在皮肤鳞癌中的发生、发展作用.方法:采用免疫组化法检测Bowen病和皮肤鳞癌皮损和正常皮肤中GRIM-19的表达.结果:正常皮肤组织中GRIM-19蛋白在表皮全层的细胞质中明显表达(7.8±3.1);在Bowen病中,GRIM-19蛋白少量表达于细胞质中,较正常皮肤组织表达明显减弱(3.2±2.8);在鳞癌组织中GRIM-19蛋白表达最弱(0.8±2.2).两两比较,差异均有统计学意义(P<0.05);三者间比较,差异也有统计学意义(P<0.05).结论:GRIM-19蛋白的减少可能在皮肤鳞癌的发生与发展过程中发挥重要作用.

Keyword :

Bowen病 皮肤鳞癌 GRIM-19

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GB/T 7714 吴娜 , 惠海英 , 郑焱 . GRIM-19在Bowen病和皮肤鳞状细胞癌组织中的表达 [J]. | 现代肿瘤医学 , 2018 , (6) : 936-938 .
MLA 吴娜 et al. "GRIM-19在Bowen病和皮肤鳞状细胞癌组织中的表达" . | 现代肿瘤医学 6 (2018) : 936-938 .
APA 吴娜 , 惠海英 , 郑焱 . GRIM-19在Bowen病和皮肤鳞状细胞癌组织中的表达 . | 现代肿瘤医学 , 2018 , (6) , 936-938 .
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TIPE1在皮肤鳞状细胞癌中的表达及意义
期刊论文 | 2018 , (18) , 2945-2947 | 现代肿瘤医学
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目的:研究TIPE1在皮肤鳞状细胞癌中的表达变化情况.方法:采用免疫组化方法检测31例皮肤鳞状细胞癌组织和31例正常皮肤组织中TIPE1的表达情况.结果:在正常皮肤组织中,TIPE1弱表达于表皮基底层及棘层下部,在表皮全层表达的阳性率为23.20%.在皮肤鳞状细胞癌中,可见TIPE1高表达于大部分的癌细胞中,阳性率为77.41%.TIPE1在皮肤鳞状细胞癌中的表达显著高于正常皮肤组织(P<0.05).结论:TIPE1可能参与皮肤鳞状细胞癌的发生和发展.

Keyword :

皮肤 皮肤鳞状细胞癌 TIPE1

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GB/T 7714 杨珮雯 , 郑焱 , 杨皎 et al. TIPE1在皮肤鳞状细胞癌中的表达及意义 [J]. | 现代肿瘤医学 , 2018 , (18) : 2945-2947 .
MLA 杨珮雯 et al. "TIPE1在皮肤鳞状细胞癌中的表达及意义" . | 现代肿瘤医学 18 (2018) : 2945-2947 .
APA 杨珮雯 , 郑焱 , 杨皎 , 李昌吉 , 王敏 , 樊文昕 et al. TIPE1在皮肤鳞状细胞癌中的表达及意义 . | 现代肿瘤医学 , 2018 , (18) , 2945-2947 .
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Yes-associated protein promotes the abnormal proliferation of psoriatic keratinocytes via an amphiregulin dependent pathway SCIE PubMed Scopus
期刊论文 | 2018 , 8 | SCIENTIFIC REPORTS
WoS CC Cited Count: 1
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Psoriasis is a chronic inflammatory skin disease with high morbidity, poor treatment methods and high rates of relapse. Keratinocyte hyperproliferation and shortened cell cycles are important pathophysiological features of psoriasis. As a known oncogene, Yes-associated protein (YAP) plays a role in promoting cell proliferation and inhibiting cell apoptosis; however, whether YAP is involved in the pathogenesis of psoriasis remains to be determined. Amphiregulin (AREG), a transcriptional target of YAP, was found to be upregulated in psoriasis, and overexpression of AREG promoted keratinocyte proliferation. In the present study, immunohistochemistry showed that YAP expression was elevated in the skin of psoriasis patients and in the Imiquimod (IMQ) mouse model of psoriasis. Knockdown of YAP in HaCaT cells inhibited cell proliferation, caused cell cycle arrest in G0/G1 phase and promoted apoptosis. These changes in YAP-knockdown HaCaT cells were related to changes in AREG expression. We concluded that YAP may play an important role in the regulation of abnormal keratinocyte proliferation via an AREG-dependent pathway and that YAP could be a new target in the treatment of psoriasis.

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GB/T 7714 Jia, Jinjing , Li, Changji , Yang, Jiao et al. Yes-associated protein promotes the abnormal proliferation of psoriatic keratinocytes via an amphiregulin dependent pathway [J]. | SCIENTIFIC REPORTS , 2018 , 8 .
MLA Jia, Jinjing et al. "Yes-associated protein promotes the abnormal proliferation of psoriatic keratinocytes via an amphiregulin dependent pathway" . | SCIENTIFIC REPORTS 8 (2018) .
APA Jia, Jinjing , Li, Changji , Yang, Jiao , Wang, Xin , Li, Ruilian , Luo, Suju et al. Yes-associated protein promotes the abnormal proliferation of psoriatic keratinocytes via an amphiregulin dependent pathway . | SCIENTIFIC REPORTS , 2018 , 8 .
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Overexpressed fibulin-3 contributes to the pathogenesis of psoriasis by promoting angiogenesis. PubMed Scopus
期刊论文 | 2018 | Clinical and experimental dermatology
SCOPUS Cited Count: 2
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Psoriasis is a chronic inflammatory skin disease. The earliest and most significant pathological change in psoriasis is angiogenesis. Fibulin-3 (Fib3) (also known as epidermal growth factor-containing fibulin-like extracellular matrix protein 1; EFEMP1) is a widely expressed extracellular matrix glycoprotein, which plays an important but contradictory role in regulating angiogenesis. However, the contribution of Fib3 to psoriasis remains unknown.To investigate the role of Fib3 in the pathogenesis of psoriasis.We first examined Fib3 expression in psoriasis cells and patient samples. We then investigated the relationship between Fib3 and angiogenesis by coculturing keratinocytes with vascular endothelial cells. Finally, we tested the therapeutic effect of a Fib3 antibody in a mouse model of psoriasis.Fib3 was overexpressed in the lesional skin of patients with psoriasis, and Fib3 levels positively correlated with psoriasis progression. Using a keratinocyte and endothelial cell coculture system, we found that keratinocyte-derived Fib3 upregulated vascular endothelial growth factor (VEGF) expression in endothelial cells and induced endothelial cell proliferation and migration. Topical application or subcutaneous injection of the Fib3 antibody decreased Psoriasis Area and Severity Index and VEGF expression in imiquimod-treated mice.Taken together, these results suggest that Fib3 is involved in the pathogenesis of psoriasis by promoting angiogenesis. Fib3 could serve as a potential target for treating psoriasis.

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GB/T 7714 Wang X , Sun X , Qu X et al. Overexpressed fibulin-3 contributes to the pathogenesis of psoriasis by promoting angiogenesis. [J]. | Clinical and experimental dermatology , 2018 .
MLA Wang X et al. "Overexpressed fibulin-3 contributes to the pathogenesis of psoriasis by promoting angiogenesis." . | Clinical and experimental dermatology (2018) .
APA Wang X , Sun X , Qu X , Li C , Yang P , Jia J et al. Overexpressed fibulin-3 contributes to the pathogenesis of psoriasis by promoting angiogenesis. . | Clinical and experimental dermatology , 2018 .
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C10orf99 contributes to the development of psoriasis by promoting the proliferation of keratinocytes SCIE PubMed Scopus
期刊论文 | 2018 , 8 | SCIENTIFIC REPORTS
WoS CC Cited Count: 2 SCOPUS Cited Count: 1
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Psoriasis is a chronic, relapsing inflammatory skin disease. The pathogenesis of psoriasis is complex and has not been fully understood. C10orf99 was a recently identified human antimicrobial peptide whose mRNA expression is elevated in psoriatic human skin samples. In this study, we investigated the functional roles of C10orf99 in epidermal proliferation under inflammatory condition. We showed that C10orf99 protein was significantly up-regulated in psoriatic skin samples from patients and the ortholog gene expression levels were up-regulated in imiquimod (IMQ)-induced psoriasis-like skin lesions in mice. Using M5-stimulated HaCaT cell line model of inflammation and a combinational approach of knockdown and overexpression of C10orf99, we demonstrated that C10orf99 could promote keratinocyte proliferation by facilitating the G1/S transition, and the pro-proliferation effect of C10orf99 was associated with the activation of the ERK1/2 and NF-kappa B but not the AKT pathways. Local depletion of C10orf99 by lentiviral vectors expressing C10orf99 shRNA effectively ameliorated IMQ-induced dermatitis. Taken together, these results indicate that C10orf99 plays a contributive role in psoriasis pathogenesis and may serve as a new target for psoriasis treatment.

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GB/T 7714 Chen, Caifeng , Wu, Na , Duan, Qiqi et al. C10orf99 contributes to the development of psoriasis by promoting the proliferation of keratinocytes [J]. | SCIENTIFIC REPORTS , 2018 , 8 .
MLA Chen, Caifeng et al. "C10orf99 contributes to the development of psoriasis by promoting the proliferation of keratinocytes" . | SCIENTIFIC REPORTS 8 (2018) .
APA Chen, Caifeng , Wu, Na , Duan, Qiqi , Yang, Huizi , Wang, Xin , Yang, Peiwen et al. C10orf99 contributes to the development of psoriasis by promoting the proliferation of keratinocytes . | SCIENTIFIC REPORTS , 2018 , 8 .
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Survivin和PI3K、AKT在寻常型银屑病皮损角质形成细胞中的表达及其相关性 CSCD PKU
期刊论文 | 2017 , (11) , 1512-1516 | 南方医科大学学报
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目的 探讨凋亡抑制蛋白Survivin和PI3K、AKT在寻常型银屑病(PV)进行期斑块状皮损角质形成细胞(KCs)中的表达水平及作用.方法 临床上收集22例PV患者进行期斑块状皮损以及18例正常皮肤组织.采用免疫组织化学、Western blot和real-time quantitative PCR等方法检测22例PV患者进行期斑块状皮损和18例正常皮肤组织中KCs的Survivin、PI3K和AKT表达,并分析它们在PV皮损KCs中的相关性.使用小干扰RNA(siRNA)在HaCaT细胞中沉默AKT,并通过Western blot实验检测Survivin的表达水平.结果 PV皮损KCs中Survivin、PI3K和AKT的蛋白表达水平均高于正常皮肤组织.PV皮损KCs中Survivin和PI3K mRNA表达成正相关(r=0.4510;P=0.0351);PV皮损KCs中Survivin和AKT mRNA表达成正相关(r=0.4423;P=0.0393);在HaCaT细胞中,沉默AKT后可引起Survivin的表达下调.结论 凋亡抑制蛋白Survivin与PI3K/AKT信号通路可能参与了PV的发生与发展.

Keyword :

Survivin AKT 寻常型银屑病 PI3K

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GB/T 7714 王昊 , 冉立伟 , 惠珂 et al. Survivin和PI3K、AKT在寻常型银屑病皮损角质形成细胞中的表达及其相关性 [J]. | 南方医科大学学报 , 2017 , (11) : 1512-1516 .
MLA 王昊 et al. "Survivin和PI3K、AKT在寻常型银屑病皮损角质形成细胞中的表达及其相关性" . | 南方医科大学学报 11 (2017) : 1512-1516 .
APA 王昊 , 冉立伟 , 惠珂 , 王新阳 , 郑焱 . Survivin和PI3K、AKT在寻常型银屑病皮损角质形成细胞中的表达及其相关性 . | 南方医科大学学报 , 2017 , (11) , 1512-1516 .
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肿瘤坏死因子超家族成员12(TNFSF12/TWEAK)在寻常型银屑病皮损组织表达增强 CSCD PKU
期刊论文 | 2017 , (10) , 1415-1418 | 细胞与分子免疫学杂志
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目的 探索肿瘤坏死因子超家族成员12/肿瘤坏死因子样凋亡微弱诱导剂(TNFSF12/IWEAK)在寻常型银屑病(PV)患者皮损组织中的表达及意义.方法 临床上收集22例PV患者进行期斑块状皮损以及18例正常皮肤组织.采用实时定量PCR检测皮肤组织TNFSF12/TWEAK的mRNA水平,Western blot法检测其蛋白水平;采用免疫组织化学染色法检测皮肤组织TNFSF12/TWEAK的表达情况.结果 PV皮损组织中TNFSF12/TWEAK的mRNA和蛋白水平高于正常皮肤组织.结论 PV皮损组织TNFSF12/TWEAK高表达.

Keyword :

免疫组织化学染色 肿瘤坏死因子超家族成员12/肿瘤坏死因子样凋亡微弱诱导剂(TNFSF12/TWEAK) 寻常型银屑病

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GB/T 7714 袁艳丽 , 冉立伟 , 惠珂 et al. 肿瘤坏死因子超家族成员12(TNFSF12/TWEAK)在寻常型银屑病皮损组织表达增强 [J]. | 细胞与分子免疫学杂志 , 2017 , (10) : 1415-1418 .
MLA 袁艳丽 et al. "肿瘤坏死因子超家族成员12(TNFSF12/TWEAK)在寻常型银屑病皮损组织表达增强" . | 细胞与分子免疫学杂志 10 (2017) : 1415-1418 .
APA 袁艳丽 , 冉立伟 , 惠珂 , 王新阳 , 郑焱 , 王昊 . 肿瘤坏死因子超家族成员12(TNFSF12/TWEAK)在寻常型银屑病皮损组织表达增强 . | 细胞与分子免疫学杂志 , 2017 , (10) , 1415-1418 .
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寻常型银屑病皮损组织中存活蛋白(survivin)和STAT2的表达增强且二者呈正相关 CSCD PKU
期刊论文 | 2017 , (9) , 1261-1265 | 细胞与分子免疫学杂志
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目的 探究凋亡抑制蛋白存活蛋白(survivin)与信号转导子和转录激活子2(STAT2)在寻常型银屑病(PV)患者进行期斑块状皮损组织中的表达及其相关性.方法 临床上收集22例PV患者进行期斑块状皮损、非皮损组织以及18例正常皮肤组织.采用实时定量PCR检测皮肤组织中survivin和STAT2 mRNA水平,Western blot法检测皮肤组织中survivin和STAT2蛋白水平;采用免疫组织化学染色法检测皮肤组织中survivin和STAT2表达情况.采用Pearson相关分析确定survivin与STAT2mRNA表达的相关性.结果 银屑病皮损组织中survivin、STAT2的mRNA和蛋白水平均高于银屑病非皮损组织和正常皮肤组织,且银屑病皮损组织中survivin、STAT2的mRNA表达呈正相关(r=0.5282).结论 Survivin、STAT2在寻常型银屑病皮损组织表达增强且二者mRNA表达水平呈正相关.

Keyword :

信号转导子和转录激活子2(STAT2) 存活蛋白(survivin) 寻常型银屑病

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GB/T 7714 王昊 , 冉立伟 , 惠珂 et al. 寻常型银屑病皮损组织中存活蛋白(survivin)和STAT2的表达增强且二者呈正相关 [J]. | 细胞与分子免疫学杂志 , 2017 , (9) : 1261-1265 .
MLA 王昊 et al. "寻常型银屑病皮损组织中存活蛋白(survivin)和STAT2的表达增强且二者呈正相关" . | 细胞与分子免疫学杂志 9 (2017) : 1261-1265 .
APA 王昊 , 冉立伟 , 惠珂 , 王新阳 , 郑焱 . 寻常型银屑病皮损组织中存活蛋白(survivin)和STAT2的表达增强且二者呈正相关 . | 细胞与分子免疫学杂志 , 2017 , (9) , 1261-1265 .
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