Gas-liquid　bubbly　flows　with　wide　range　of　bubble　sizes　are　commonly　encountered　in　many　industrial　applications.　Based　on　our　previous　study,　a　generalized　Average　Bubble　Number　Density　(ABND)　model　has　been　developed　to　model　the　dynamical　changes　of　bubble　size　due　to　bubble　coalescence　and　breakage　mechanism.　With　the　aim　to　asses　the　model　performance,　numerical　studies　have　been　performed　to　validate　the　model　predictions　against　experimental　data.　Three　experimental　data　[7,10,12]　exhibiting　totally　different　bubble　size　evolution　trends　were　strategically　selected　for　the　present　validation　study.　Numerical　predictions　were　validated　against　measured　results　under　three　different　experimental　conditions.　In　general,　predictions　of　the　ABND　model　yield　good　agreement　with　experimental　data.　The　encouraging　results　demonstrated　the　capability　of　the　ABND　model　in　capturing　the　changes　of　bubbles　size　due　to　bubble　interactions　and　the　transition　from　＂wall　peak＂　to　＂core　peak＂　gas　volume　fraction　profiles　under　various　flow　conditions.　Merits　and　drawbacks　of　the　ABND　model　for　industrial　application　are　also　discussed.