Effects　of　key　adhesive　parameters　such　as　curing　temperature　and　the　amount　of　adhesive　on　the　out-of-plane　compression　and　fatigue　strength　of　sandwich　panels　with　pyramidal　core　are　experimentally　investigated　and　compared　with　those　of　theoretical　analysis.　It　is　shown　that　two　different　curing　temperatures　lead　to　the　different　liquidity　of　surplus　adhesive　squeezed　out　and　then　the　shapes　of　spew　fillet.　Sandwich　panels　with　arc　spew　fillets　have　higher　compression　strength　than　those　with　rounded　spew　fillets.　With　the　increase　of　the　amount　of　adhesive,　the　out-of-plane　compression　strength　of　those　sandwich　panels　clearly　increases　firstly　and　then　gradually　tends　to　the　theoretical　value.　By　analysis　of　the　S-N　fatigue　curves　of　four　types　of　sandwich　specimens,　the　shape　of　spew　fillet,　the　amount　of　adhesive　and　the　loading　ratios　are　identified　as　the　key　factors　governing　the　compression　fatigue　properties　of　truss-cored　sandwich　structures.　©　2018　Elsevier　Ltd