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Author:

马君择 (马君择.)

Abstract:

目的:本研究通过建立体外培养牛眼小梁细胞(bovine trabecular meshwork cell, TM cell)的方法,观察转化生长因子-β1(Transforming Growth Factor-β1, TGF-β1)对体外培养的牛眼小梁细胞的生长抑制作用和胶原合成的增强作用,并且初步研究tranilast对TGF-β1的对抗作用,从而探讨TGF-β1对房水引流的调节作用及在青光眼的发病机制中的意义。对tranilast从发病学环节治疗青光眼的可能性进行初步研究,为青光眼的临床用药开辟一条新

Keyword:

MTT法 tranilast 牛眼小梁细胞 培养 羟脯氨酸 细胞生长 细胞外间质 转化生长因子-β1

Author Community:

  • [ 1 ] 西安交通大学医学部

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Basic Info :

Degree: 硕士

Mentor: 张德秀

Student No.:

Year: 2003

Language: Chinese

Cited Count:

WoS CC Cited Count: 0

SCOPUS Cited Count:

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 2

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