Background:　The　hepatocellular　carcinoma　is　very　common　in　China.　Our　aim　in　this　report　was　to　investigate　clinical　and　pathological　factors　based　on　the　current　decade　data　that　could　influence　prognosis　of　HCC　patients　after　hepatectomy.　Methods:　Between　2002　and　2009,　all　patients　undergoing　hepatectomy　for　HCC　were　followed　up　and　reviewed　retrospectively.　Prognostic　factors　were　studied　by　univariate　and　multivariate　analysis,　with　Kaplan-Meier　and　Cox　multivariate　survival　analyses.　Results:　Complete　clinicopathologic　and　follow-up　data　were　available　for　114　patients.　The　estimated　cumulative　survival　rates　at　1,　3,　and　5　yr　were　84.6%,　60.2%　and　51.8%,　respectively.　On　univariate　analysis,　key　prognostic　factors　were　AFP　level,　GGT　level,　tumor　size,　number　of　tumors,　portal　vein　invasion,　liver　cirrhosis　status　and　TNM　stage.　In　the　multivariate　analysis,　tumor　size,　GGT　level,　liver　cirrhosis　status　and　portal　vein　invasion　were　significantly　associated　with　patients＇　prognosis.　Conclusion:　Through　follow-up　of　a　relatively　large　cohort　of　Chinese　patients,　tumor　size,　GGT　level,　liver　cirrhosis　status,　portal　vein　invasion　were　revealed　as　important　factors　for　long-term　survival　after　hepatectomy.　Early　diagnosis　for　tumor　and　the　improvement　of　liver　function　before　surgery　are　important　ways　to　improve　the　prognosis.