BACKGROUND　Simultaneous　removal　of　arsenic　and　fluoride　anions　from　water　by　adsorption　remains　a　challenge　for　environmental　remediation　practice.　To　address　this　issue,　four　mesoporous　bimetallic　oxides　(MBOs)　were　prepared　via　the　evaporation-induced　self-assembly　(EISA)　method　and　studied　as　adsorbents　for　the　co-uptake　of　arsenate　(As(V))　and　fluoride　(F-)　from　synthetic　wastewater.　Adsorption　envelope　and　equilibrium　experiments　were　performed　to　investigate　the　adsorption　behaviors　and　properties.　RESULTS　These　composites　possessed　high　surface　areas　(e.g.　200　m(2)　g(-1)　for　meso-Ti/Al)　and　well-defined　mesopores,　enabling　high　adsorption　capacities　for　both　As(V)　and　F-.　The　maximum　adsorption　capacities　of　mesoporous　titanium-lanthanum　oxide　(meso-Ti/La)　were　as　high　as　81.42　mg　g(-1)　and　44.37　mg　g(-1)　for　As(V)　and　F-,　respectively.　Surface　complexation　modeling　indicates　that　As(V)　removal　mainly　involved　bidentate　surface　complexation　with　surface　equivalent　to　Me-OH,　while　F-　was　retained　by　formation　of　monodentate　surface　complexes.　CONCLUSION　The　removal　mechanisms　were　confirmed　by　X-ray　photoelectron　spectroscopy.　These　MBOs　were　found　to　be　effective　for　simultaneous　removal　of　arsenic　and　fluoride　from　water.　This　study　also　demonstrated　that　the　incorporation　of　multi-components　and　mesoporosity　into　one　composite　is　an　efficient　strategy　for　design　and　application　of　high-efficiency　adsorbents　for　environmental　remediation　of　aqueous　contaminants.　(c)　2018　Society　of　Chemical　Industry