In　this　paper,　a　glow-like　helium　atmospheric　pressure　plasma　jet　is　combined　with　clinical　antitumor　drug-Tegafur-　to　treat　pancreatic　tumor　cells　in　vitro.　The　results　reveal　that　they　have　a　synergistic　effect　on　inhibiting　the　proliferation　of　tumor　cells　when　the　plasma　is　applied　before　the　drug,　but　the　antagonism　between　drug　and　plasma　meets　in　the　other　case.　The　results　are　hopeful　to　promote　the　application　of　the　plasma　combining　the　drugs　in　clinic　therapy　for　cancer.