Asthma　has　affected　more　than　300　million　people　worldwide　and　is　considered　one　of　the　most　debilitating　global　public　health　problems　based　on　a　recent　statistical　report　from　the　Global　Initiative　for　Asthma.　Inflammation　of　the　airways　leads　to　the　various　interrelated　mechanisms　of　innate　and　adaptive　immunity　acting　mutually　with　the　epithelium　of　the　respiratory　organ.　Fucoxanthin　is　an　orange　or　brown　pigment　which　is　naturally　found　in　various　seaweeds.　To　the　best　of　our　knowledge,　there　are　no　scientific　claims　or　evidence　of　the　curative　effects　of　fucoxanthin　against　asthma.　Hence,　this　present　research　was　designed　to　investigate　the　curative　activity　of　fucoxanthin　against　ovalbumin-induced　asthma　in　a　mouse　model.　Fucoxanthin　(50　mg/kg)　showed　significant　(P　＜　0.001)　antiasthma　activity.　It　effectively　decreased　intracellular　secretion　of　reactive　oxygen　species　and　increased　antioxidant　enzyme　activity.　Fucoxanthin　also　decreased　inflammatory　cytokine　markers　in　bronchoalveolar　lavage　fluid.　Because　fucoxanthin　showed　effective　antiasthma　activity　against　ovalbumin-induced　asthma　in　experimental　animals,　further　research　on　this　natural　antioxidant　could　lead　to　development　of　a　novel　drug　for　the　treatment　of　asthma　in　humans.