CuSO4/TiO2　catalysts　with　high　catalytic　activity　and　excellent　resistant　to　SO2　and　H2O,　were　thought　to　be　promising　catalysts　used　in　Selective　catalytic　reduction　of　nitrogen　oxides　by　NH3.　The　performance　of　catalysts　is　largely　affected　by　calcination　temperature.　Here,　effects　of　calcination　temperature　on　physicochemical　property　and　catalytic　activity　of　CuSO4/TiO2　catalysts　were　investigated　in　depth.　Catalyst　samples　calcined　at　different　temperatures　were　prepared　first　and　then　physicochemical　properties　of　the　catalyst　were　characterized　by　N2　adsorption-desorption,　X-ray　diffraction,　thermogravimetric　analysis,　Raman　spectra,　Fourier-transform　infrared　spectroscopy,　X-ray　photoelectron　spectroscopy,　temperature-programmed　desorption　of　NH3,　temperature-programmed　reduction　of　H2　and　in　situ　diffuse　reectance　infrared　Fourier　transform　spectroscopy.　Results　revealed　that　high　calcination　temperature　had　three　main　effects　on　the　catalyst.　First,　sintering　and　anatase　transform　into　rutile　with　increase　of　calcination　temperature,　causing　a　decrement　of　specific　surface　area.　Second,　decomposition　of　CuSO4　under　higher　calcination　temperature,　resulting　in　disappears　of　Brønsted　acid　sites　(S–OH),　which　had　an　adverse　effect　on　surface　acidity.　Third,　CuO　from　the　decomposition　of　CuSO4　changed　surface　reducibility　of　the　catalyst　and　favored　the　process　of　NH3　oxidation　to　nitrogen　oxides　(NOx).　Thus,　catalytic　activity　of　the　catalyst　calcined　under　high　temperatures　(≥600°C)　decreased　largely.　©　2020