Designing　a　low-cost,　high-efficiency　and　robust　doped-carbon-based　oxygen　reduction　reaction　electrocatalyst　for　large-scale　implementations　of　fuel　cells　is　highly　desirable　but　challenging.　In　this　work,　we　report　a　new　type　of　hollow　Fe3O4　with　oxygen　vacancy　incorporating　on　mesoporous　carbon　prepared　by　pyrolyzing　mesoporous　carbon　enriched　with　oxygen-containing　functional　groups,　in　combination　with　ferric　acetylacetonate.　The　catalysts　possess　high　specific　surface　area　with　predominantly　mesoporous　architecture　and　ultrahigh　nitrogen　content　(up　to　7.47　wt%).　Benefiting　from　the　integration　of　abundant　active　nitrogen　and　Fe-Nx　species,　and　synergistic　effect　between　Fe3O4　nanoparticles　cooperated　with　oxygen　vacancy　and　N-doped　carbon,　the　half-wave　potential　of　the　preparing　hybrid　catalyst　is　30　mV　more　positive　than　that　of　the　commercial　Pt/C　catalyst　in　alkaline　medium,　and　exhibits　a　high　selectivity　(4　e−　process),　and　outstanding　long-term　stability.　More　importantly,　the　C-FePPDA-900　catalyst　displays　a　high　power　density　(106　mW　cm−2)　and　specific　capacity　of　724　mAh　gzn−1　when　it　is　used　as　an　air　cathode　catalyst　in　a　specifically　assembling　Zn-air　cell,　superior　to　those　of　most　reported　catalysts.　©　2020