For　the　general　time-consuming　problem　of　3D　time-domain　blade　vibration　calculation　by　fluid-solid　coupling,　the　modal　displacement　of　a　kind　of　hypothetical　global　structure　is　adopted　to　calculate　the　time-domain　response　of　solid　and　complete　the　fluid　mesh　deformation　effectively,　so　a　Global-Elastic-Structure　method　for　3D　time-domain　fluid-solid　coupling　analysis　is　developed,　which　is　applied　to　the　aerodynamic　stability　analysis　of　compressor　blades　on　0°　inter　blade　phase　angle　(IBPA)　and　180°　IBPA.　The　results　show　that　the　calculated　results　by　the　proposed　method　are　mainly　consistent　with　those　of　traditional　two-way　time-domain　method　and　literatures,　while　the　calculation　efficiency　improves　significantly　compared　to　the　traditional　method.　On　the　two　IBPAs　involved,　the　aerodynamic　dampings　of　blade　vibration　both　increase　first　and　then　drop　with　the　decrease　of　the　flow-rate,　the　aerodynamic　stability　of　the　blade　on　180°IBPA　is　greatly　improved　compared　with　that　of　0°IBPA,　indicating　that　the　proposed　method　can　be　effectively　applied　to　the　engineering　fluid-solid　coupling　analysis　of　blades.　©　2020,　Editorial　Department　of　Journal　of　Propulsion　Technology.　All　right　reserved.