Hypothesis:　Controlling　the　wetting　behaviour　of　gallium-based　liquid　metal　is　highly　desired　for　soft　electronics　applications.　Currently,　achieving　durable　and　patternable　liquid-metal-repellent　surfaces　by　a　simple　and　flexible　method　is　challenging.　The　femtosecond　laser　has　a　remarkable　ability　to　modify　the　morphology　and　wettability　of　a　solid　surface.　It　can　also　potentially　be　applied　to　control　the　wettability　of　liquid　metal　and　achieve　complete　liquid-metal　patterns.　Experiments:　Femtosecond　laser　processing　was　used　to　form　a　microstructure　on　a　polydimethylsiloxane　(PDMS)　surface.　With　regard　to　the　laser-ablated　surface,　its　morphology　was　observed　by　a　scanning　electron　microscope,　and　its　wettability　to　liquid　metal　was　characterized　by　measuring　the　contact　angle,　sliding　angle,　and　adhesive　force.　Finally,　its　potential　applications　in　soft　electronics　were　demonstrated.　Findings:　A　layer　of　micro/nanostructures　was　directly　prepared　on　the　PDMS　surface　by　laser　ablation,　presenting　excellent　liquid-metal　repellence.　Without　expensive　masks　and　complex　operation　processes,　programmable　liquid-metal-repellent　patterns　were　easily　obtained　by　femtosecond　laser　selectively　treating　the　PDMS　surface,　enabling　EGaIn　to　be　patterned　on　the　textured　surface.　The　as-prepared　liquid-metal　patterns　can　be　used　as　a　flexible　microheater　and　a　microstrip　patch　antenna.　It　is　believed　that　laser-patterned　liquid-metal-repellent　surfaces　will　have　significant　applications　in　soft　electronics,　such　as　antennas,　microcircuits,　lab　on　chips,　and　wearable　electronic　devices.　©　2020　Elsevier　Inc.