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Author:

Meng, Du (Meng, Du.) | Chai, Yan-Lan (Chai, Yan-Lan.) | He, Yin-Fang (He, Yin-Fang.) | Hu, Honglian (Hu, Honglian.) | Liu, Rui (Liu, Rui.) | Liu, Zi (Liu, Zi.)

Indexed by:

SCIE PubMed Scopus

Abstract:

Solid tumors following myelodysplastic syndrome (MDS) are rare and have no uniform treatment guidelines. The current study presents a rare case of a 47-year-old female diagnosed with cervical cancer (International Federation of Gynecology and Obstetrics stage IIIB) with an eight-year history of MDS. A multidisciplinary treatment discussion was organized and a rigorous treatment plan was developed. With injection of granulocyte colony-stimulating factor and interleukin-11 factor, transfusion of red blood cell suspension and close monitoring of the blood count, the patient was administered radiotherapy, specifically intensity modulated radiation therapy. However, a degree IV bone marrow suppression repeatedly assaulted, leading to interruption of the radiotherapy treatment. Eventually, the total dose received by point A (2 cm above the cervical os marker and 2 cm perpendicular to the uterine axis along the plane of the uterus) was 51 Gy. One month later, a gynecological examination and magnetic resonance imaging of the pelvis revealed that the treatment resulted in a complete remission. In conclusion, radiation therapy can still be implemented to obtain satisfactory local control when the hematopoietic function of the bone marrow is weakened due to long-term MDS.

Keyword:

cervical carcinoma myelodysplastic syndrome treatment

Author Community:

  • [ 1 ] [Meng, Du; Chai, Yan-Lan; Liu, Rui; Liu, Zi] Xi An Jiao Tong Univ, Affiliated Hosp 1, Dept Radiotherapy Oncol, Xian 710061, Shaanxi, Peoples R China
  • [ 2 ] [He, Yin-Fang] Shangluo Cent Hosp, Dept Gynaecol, Shangluo 726000, Shaanxi, Peoples R China
  • [ 3 ] [Hu, Honglian] Xi An Jiao Tong Univ, Dept Blood Pathol, Affiliated Hosp 1, Xian 710061, Shaanxi, Peoples R China

Reprint Author's Address:

  • Xi An Jiao Tong Univ, Affiliated Hosp 1, Dept Radiotherapy Oncol, 277 Yanta West Rd, Xian 710061, Shaanxi, Peoples R China.

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Source :

ONCOLOGY LETTERS

ISSN: 1792-1074

Year: 2014

Issue: 1

Volume: 8

Page: 82-84

1 . 5 5 4

JCR@2014

2 . 9 6 7

JCR@2020

ESI Discipline: CLINICAL MEDICINE;

ESI HC Threshold:188

JCR Journal Grade:4

CAS Journal Grade:4

Cited Count:

WoS CC Cited Count: 1

SCOPUS Cited Count: 2

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 13

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