Orthogonal　frequency　division　multiplexing　(OFDM)　has　been　selected　as　a　5G　New　Radio　(NR)　waveform　for　carrier　frequency　below　40　GHz.　In　order　to　satisfy　the　low　peak-to-average　power　ratio　(PAPR)　requirement　for　high　power　amplifier　(PA)　efficiency,　OFDM　with　PAPR　reduction　is　highly　desirable.　In　this　paper,　we　evaluate　the　performance　of　OFDM　with　various　receiver　agnostic　PAPR　reduction　techniques　in　the　presence　of　hardware　impairments.　The　evaluations　are　performed　in　hardware-in-the-loop　trials.　The　measurement　results　showed　that　in　case　of　nonlinear　PA　and　high　power　transmission,　OFDM　with　PAPR　reduction　schemes　can　effectively　reduce　the　PAPR　of　OFDM　signals　and　can　achieve　similar　performance　as　compared　to　DFT-spread-OFDM,　thus　OFDM　with　simple　PAPR　reduction　is　a　viable　option　for　5G　NR　waveform.　©　2020　IEEE.