Aims　and　background:　Breast　cancer　is　one　of　the　most　common　neoplasms　among　women　in　many　developing　countries　including　China,　and　is　the　leading　cause　of　female　cancer-related　deaths　worldwide.　Methods:　In　the　current　study,　we　analyzed　the　relationship　between　14　tag　single-nucleotide　polymorphisms　(tSNPs)　and　breast　cancer　risk　in　the　Han　Chinese　population　including　185　breast　cancer　patients　and　199　healthy　women　controls　on　the　different　types　of　breast　cancer　and　menopausal　status.　Results:　Overall,　we　found　rs2981579　in　the　FGFR2　gene,　and　rs2380205　were　associated　with　breast　cancer　susceptibility.