Aim　To　investigate　the　predictive　factors　of　pulmonary　arterial　hypertension　(PAH)　in　systemic　lupus　erythematosus　(SLE)　patients.　Method　This　chart　review　study　included　408　SLE　patients.　We　defined　PAH　as　2　consecutive　systolic　pulmonary　arterial　pressure　(PAP)　values　＞=　40　mm　Hg　by　echocardiography.　Demographic　characteristics,　clinical　symptoms,　autoantibodies,　and　laboratory　tests　were　studied.　Results　Thirty-four　patients　in　the　SLE/PAH+　group　and　374　patients　in　the　SLE/PAH-　group　were　analyzed.　The　prevalence　of　PAH　in　SLE　is　8.3%　in　this　study.　The　occurrences　of　interstitial　pneumonitis,　polyserositis　and　myocardial　damage　were　higher　in　the　SLE/PAH+　group　(P　=　.001,　P　=　.033　and　P　＜　.001,　respectively).　The　occurrence　of　anti-double-stranded　DNA　and　anti-ribosomal　RNA　protein　(anti-rRNP)　antibodies　were　lower　in　the　SLE/PAH+　group　(P　=　.003,　.010).　Positive　rates　of　anti-Sjogren＇s　syndrome　antigen　A　(anti-SSA)/Ro52　antibodies　and　anti-SSB　antibodies　were　higher　in　the　SLE/PAH+　group　(P　=　.046,　.021).　C-reactive　protein　and　immunoglobin　G　(IgG)　were　higher　in　the　SLE/PAH+　group　(P　=　.009,　.005).　Ejection　fraction　and　SLE　disease　activity　index　between　the　2　groups　had　no　differences.　Multivariable　logistic　regression　indicated　that　interstitial　pneumonitis,　myocardial　damage　and　high　IgG　are　predictive　factors　for　SLE-associated　PAH　patients.　Conclusion　From　this　study,　we　found　that　interstitial　pneumonitis,　myocardial　damage,　and　high　IgG　were　predictive　factors　of　PAH　in　SLE　patients.