During　the　power　operation　of　PWR,　due　to　burnup　effect　and　boronation　effect,　the　abundance　of　10B　in　the　primary　circuit　boric　acid　solution　will　change　continuously　with　time,　and　the　nuclear　power　plant　can　not　provide　the　real-time　measured　value　of　10B　abundance.　As　a　result,　the　calculated　value　of　the　critical　boron　concentration　in　the　nuclear　design　program　is　lower　than　the　measured　value　in　the　middle　of　the　cycle.　Therefore,　in　order　to　reduce　the　deviation　between　the　calculated　value　and　the　measured　value　of　the　critical　boron　concentration　in　the　primary　circuit　of　the　core,　this　paper　gives　a　calculation　method　of　10B　abundance　based　on　the　Bamboo-C　software　independently　developed　by　the　Nuclear　Engineering　Computational　Physics　(NECP)　Laboratory　of　Xi＇an　Jiaotong　University.　This　method　can　consider　the　influence　of　burnup　effect　and　boronation　effect　on　the　critical　boron　concentration　at　the　same　time.　Using　the　10B　abundance　calculation　method　mentioned　in　this　paper,　the　power　operation　history　of　the　M310　unit　of　Fuqing　NPP　was　tracked　and　simulated,　and　the　calculated　values　of　the　primary　circuit　critical　boron　concentration　and　B-10　abundance　were　compared　and　verified　with　the　measured　values.　The　verification　results　show　that　the　10B　abundance　calculation　method　mentioned　in　this　paper　can　improve　the　numerical　calculation　results　of　core　critical　boron　concentration,　and　has　the　conditions　for　industrial　application.　Copyright　©2022　Nuclear　Power　Engineering.　All　rights　reserved.