Indole　is　one　of　refractory　intermediate　products　in　hydrothermal　conversion　of　biomass,　and　its　decomposition　significantly　restricts　the　improvement　of　gasification　efficiency　and　hydrogen　production　in　biomass　supercritical　water　gasification　(SCWG).　In　order　to　improve　gasification　efficiency　of　indole　and　moderate　reaction　conditions　for　hydrogen　production　in　biomass　SCWG,　indole　(0.25　mol/L)　was　gasified　in　supercritical　water　at　540–600　°C,　25　MPa,　0–0.8　of　oxidation　coefficients　(OC)　in　min-batch　reactors.　Corresponding　pathways　and　kinetics　of　partial　oxidation　of　indole　in　supercritical　water　for　hydrogen　production　were　explored.　The　results　showed　that　the　addition　of　oxidant　(hydrogen　peroxide)　promoted　steam　reform　and　decomposition,　especially　ring-opening　reactions,　so　increasing　the　gasification　efficiency　of　indole　and　the　yields　of　H2　and　CO2　in　gaseous　products.　The　maximum　hydrogen　gasification　efficiency　could　reach　up　to　60.3%　at　OC　=　0.6,　which　was　about　twice　that　of　non-oxidant.　Moreover,　29　groups　of　reaction　rate　constants,　activation　energies　and　Arrhenius　constants　were　obtained　in　the　established　kinetic　model.　©　2022　Elsevier　B.V.