Aside　from　ultrahigh　strength　and　elasticity,　metallic　glasses　(MGs)　possess　a　number　of　favorable　properties.　However,　their　lack　of　dislocation　based　plastic　deformation　mechanisms　in　crystalline　metals　and　the　resulting　loss　of　ductility　have　restricted　the　engineering　applications　of　MGs　over　the　last　60　years.　This　review　aims　to　provide　an　overview　of　deformation　and　failure　mechanisms　of　MGs　via　formation　and　propagation　of　shear　bands　(SBs),　with　an　emphasis　on　the　control　of　SBs　to　promote　strength-ductility　synergy.　With　this　goal　in　mind,　we　highlight　some　of　the　emerging　strategies　to　improve　the　ductility　of　MGs.　Topics　covered　include　postprocessing　techniques　such　as　precompression,　heterogeneity　tuning,　and　rejuvenation,　with　a　primary　focus　on　recent　progresses　in　structural　design　based　methods　including　nanoglasses,　notched　MGs,　and　MG　nanolattices,　as　future　innovations　toward　strength-ductility　synergy　beyond　the　current　benchmark　ranges.　Copyright　©　2023　by　ASME.