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Author:

Guo, Junde (Guo, Junde.) | Li, Yue (Li, Yue.) | Li, Yu (Li, Yu.) | Lu, Hailin (Lu, Hailin.) | Qin, Liguo (Qin, Liguo.) | Hua, Meng (Hua, Meng.) | Dong, Guangneng (Dong, Guangneng.)

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SCIE EI Scopus

Abstract:

Excessive wear debris in prosthesis tends to induce loosening, which is a major problem affecting the durability of long-serving implants. Although bionic synovial fluid can be used to improve the lubrication of artificial joints, the fluid is often absorbed easily by the tissues of human body. To enhance the effectiveness of bionic synovial fluid, poly(epsilon-caprolactone)-poly(ethylene glycol)-poly(epsilon-caprolactone) (PCEC) hydrogel was prepared as a carrier for the bovine serum albumin (BSA) in synovial fluid. It thus significantly reduces the loss rate of BSA. Experimental results show that the good sustainability and favorable release ability of hydrogel efficiently prevent the rapid outflowing of BSA. Experiments also reveal that the PCEC hydrogel inclines to form a particular structure with BSA and thus give BSA an excellent slow-release performance. Furthermore, friction and wear tests indicate that the released solution from the PCEC hydrogel possesses good lubricating properties. In general, the average friction coefficient of released solution is approximatively 77% lower than that of the normal phosphate-buffered solution. This study furnishes with an effective approach to prolong the lubricating duration of BSA in artificial prostheses.

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Author Community:

  • [ 1 ] [Guo, Junde; Li, Yue; Lu, Hailin; Qin, Liguo; Dong, Guangneng] Xi An Jiao Tong Univ, Educ Minist, Key Lab Modern Design & Rotor Bearing Syst, Xian 710049, Shaanxi, Peoples R China
  • [ 2 ] [Li, Yu] Xi An Jiao Tong Univ, Sch Sci, Dept Appl Chem, Xian 710049, Shaanxi, Peoples R China
  • [ 3 ] [Hua, Meng] City Univ Hong Kong, Dept Mech & Biomed Engn, Kowloon, Hong Kong, Peoples R China
  • [ 4 ] [Guo, Junde]Xi An Jiao Tong Univ, Educ Minist, Key Lab Modern Design & Rotor Bearing Syst, Xian 710049, Shaanxi, Peoples R China
  • [ 5 ] [Li, Yue]Xi An Jiao Tong Univ, Educ Minist, Key Lab Modern Design & Rotor Bearing Syst, Xian 710049, Shaanxi, Peoples R China
  • [ 6 ] [Lu, Hailin]Xi An Jiao Tong Univ, Educ Minist, Key Lab Modern Design & Rotor Bearing Syst, Xian 710049, Shaanxi, Peoples R China
  • [ 7 ] [Qin, Liguo]Xi An Jiao Tong Univ, Educ Minist, Key Lab Modern Design & Rotor Bearing Syst, Xian 710049, Shaanxi, Peoples R China
  • [ 8 ] [Dong, Guangneng]Xi An Jiao Tong Univ, Educ Minist, Key Lab Modern Design & Rotor Bearing Syst, Xian 710049, Shaanxi, Peoples R China
  • [ 9 ] [Li, Yu]Xi An Jiao Tong Univ, Sch Sci, Dept Appl Chem, Xian 710049, Shaanxi, Peoples R China
  • [ 10 ] [Hua, Meng]City Univ Hong Kong, Dept Mech & Biomed Engn, Kowloon, Hong Kong, Peoples R China

Reprint Author's Address:

  • Xi An Jiao Tong Univ, Educ Minist, Key Lab Modern Design & Rotor Bearing Syst, Xian 710049, Shaanxi, Peoples R China.; Hua, M (reprint author), City Univ Hong Kong, Dept Mech & Biomed Engn, Kowloon, Hong Kong, Peoples R China.

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Source :

JOURNAL OF MATERIALS SCIENCE

ISSN: 0022-2461

Year: 2017

Issue: 20

Volume: 52

Page: 12054-12066

2 . 9 9 3

JCR@2017

4 . 2 2 0

JCR@2020

ESI Discipline: MATERIALS SCIENCE;

ESI HC Threshold:217

JCR Journal Grade:2

CAS Journal Grade:3

Cited Count:

WoS CC Cited Count: 8

SCOPUS Cited Count: 10

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 5

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