Transcranial　magnetic　stimulation　(TMS)　is　a　non-invasive　nerve　stimulation　technique　that　has　been　widely　used　in　clinical　treatment　in　recent　years.　Compared　with　traditional　single-channel　magnetic　stimulation　coil,　multi-channel　coil　array　has　shown　more　attractive　capacities　to　achieve　multi-point　synchronous　stimulation,　scanning　stimulation,　and　flexible　switch　of　various　stimulation　patterns.　However,　the　driving　and　controlling　methods　of　the　multi-channel　TMS　require　further　investigations　due　to　the　design　complexity　of　the　driving　circuits　and　the　electromagnetic　coupling　of　multi-coils.　A　driving　and　controlling　circuit　was　designed　based　on　the　4×4　straight-wire　array　in　this　paper.　The　driving　circuit　was　designed　to　generate　the　pulse　current,　mainly　consisting　of　one　capacitor　charging　segment　and　eight　discharging　segments.　The　stimulating　pattern,　amplitude　and　repetitive　frequency　of　the　stimulating　current　could　be　flexibly　adjusted　through　the　controlling　circuit.　By　theoretical　calculation　and　experimental　measurement,　the　effect　of　electromagnetic　coupling　on　current　was　analyzed.　The　experimental　results　also　illustrated　the　ability　for　achieving　the　adjustment　of　the　repetitive　frequency　and　stimulating　pattern.　The　stimulating　strength　below　the　coil　array　(3cm)　was　theoretically　proved　exceeding　the　excitation　threshold　of　brain　cells.　©　2017,　The　editorial　office　of　Transaction　of　China　Electrotechnical　Society.　All　right　reserved.