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Author:

Wang Jian-Ye (Wang Jian-Ye.) | Liu Ming (Liu Ming.) | Zhang Yao-Guang (Zhang Yao-Guang.) | Zeng Ping (Zeng Ping.) | Ding Qiang (Ding Qiang.) | Huang Jian (Huang Jian.) | He Da-Lin (He Da-Lin.) | Song Bo (Song Bo.) | Kong Chui-Ze (Kong Chui-Ze.) | Pang Jian (Pang Jian.)

Indexed by:

SCIE

Abstract:

Background The enlarged prostate leads to obstruction and lower urinary tract symptoms (LUTS), which comprise frequency, urgency, weak stream, straining and nocturia. This study was conducted in a large series of patients to evaluate the relationship between LUTS as stipulated in the International Prostate Symptom Score (IPSS) and the objective parameters related to benign prostatic hyperplasia (BPH). Methods We enrolled 1295 BPH patients from seven centers. The patients were either at first diagnosis of BPH or had discontinued medical treatment for at least 3 months. Those with several other diseases that may be potential risk factors affecting urinary symptoms were excluded from the study. Age, IPSS, prostate volume, peak flow rate, urine volume and post-voiding residual urine volume were measured. The relationship between IPSS and objective parameters were quantified by means of Spearman correlation coefficients. The differences in these parameters between the groups with mild, moderate or severe symptoms were also evaluated. Results Statistically significant correlations were found between IPSS and objective parameters by means of Spearman correlation coefficients. When the patients were divided into three groups with different severities of symptoms, there were significant differences in peak flow rate, urine volume, prostate volume, residue urine volume and quality of life, whereas average age and prostate-specific antigen levels were similar. However, there was evident overlap of these parameters between the groups. The same results were found when the irritative or obstructive subscore of IPSS was considered. Conclusions The correlation between objective parameters of BPH and LUTS is significant. However, it is hard to predict the severity of symptoms by these parameters.

Keyword:

benign prostatic hyperplasia international prostate symptom score lower urinary tract symptoms

Author Community:

  • [ 1 ] [Wang Jian-Ye; Liu Ming; Zhang Yao-Guang] Beijing Hosp, Dept Urol, Beijing 100730, Peoples R China
  • [ 2 ] [Zeng Ping] Beijing Hosp, Inst Geriatr, Beijing 100730, Peoples R China
  • [ 3 ] [Ding Qiang] Fudan Univ, Huashan Hosp, Dept Urol, Shanghai 200040, Peoples R China
  • [ 4 ] [Huang Jian] Sun Yat Sen Univ, Affiliated Hosp 2, Dept Urol, Guangzhou 510120, Guangdong, Peoples R China
  • [ 5 ] [He Da-Lin] Xian Jiaotong Univ, Hosp 1, Dept Urol, Xian 710061, Shaanxi, Peoples R China
  • [ 6 ] [Song Bo] Third Mil Med Univ, Southwest Hosp, Dept Urol, Chongqing 400038, Peoples R China
  • [ 7 ] [Kong Chui-Ze] China Med Sci, Clin Hosp 1, Dept Urol, Shenyang 110001, Liaoning, Peoples R China
  • [ 8 ] [Pang Jian] Sun Yat Sen Univ, Affiliated Jiangmen Hosp, Dept Urol, Jiangmen 529070, Guangdong, Peoples R China

Reprint Author's Address:

  • Beijing Hosp, Dept Urol, Beijing 100730, Peoples R China.

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Source :

CHINESE MEDICAL JOURNAL

ISSN: 0366-6999

Year: 2008

Issue: 20

Volume: 121

Page: 2042-2045

0 . 8 5 8

JCR@2008

2 . 6 2 8

JCR@2020

ESI Discipline: CLINICAL MEDICINE;

JCR Journal Grade:3

CAS Journal Grade:4

Cited Count:

WoS CC Cited Count: 17

SCOPUS Cited Count:

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count: -1

Chinese Cited Count: -1

30 Days PV: 6

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