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Author:

Cao, Yuan (Cao, Yuan.) | Wu, Shuang (Wu, Shuang.) | Zhang, Liyu (Zhang, Liyu.) | Yang, Ying (Yang, Ying.) | Cao, Sancheng (Cao, Sancheng.) | Li, Qiao (Li, Qiao.)

Indexed by:

SCIE PubMed

Abstract:

Background: The co-existence of allergic rhinitis (AR) and obstructive sleep apnea (OSA) is a common phenomenon in clinical practice. AR has long been considered a risk factor for OSA. However, the relationship is not completely clear. Therefore, we conducted a meta-analysis to evaluate the prevalence of AR in sleep-disordered breathing (SDB) /OSA and their relationship. Methods: A comprehensive literature search was performed in PubMed/Medline, Google Scholar, Wiley Online Library, EMBASE, and Web of Science. Data were analyzed and pooled to estimate effect size (ES) /odds ratio (OR) with 95% confidence intervals (95% CI). Heterogeneity was quantified and evaluated by chi-squared-based Q-test and 12 test, with P <.05 and Ir > 50% indicating evidence of heterogeneity. Results: 44 studies contained 6086 participants were included in this meta-analysis. For adults, the prevalence of AR was 22.8 (95% CI, 15.0-30.6) % in SDB and 35.2 (95% CI, 25.6-44.7) % in OSA. In children with SDB and OSA, the prevalence of AR was /10.8 (95% CI, 24.3-57.2) %, and 45.2 (95% Cl. 25A-65.0) % respectively. The odds ratios of prevalence of the SDB pediatric patients with AR was 2.12 (959/0CI, 1.75, 2.57; P <.0001) times higher than that of non-SDB pediatric patients. There were no significant differences between OSA adults with or without AR in BMI (Body Mass Index), neck circumference, apnea hypopnea index (AHI) and epworth sleep scale score (ESS). Conclusion: The prevalence of AR in OSA/SDB is considerably high and children with SDB suffering from a higher incidence of AR than non-SDB. OSA adults accompanied with AR do not have any influences on sleep parameters.

Keyword:

allergic rhinitis apnea hypopnea index body mass index Epworth Sleep Scale score meta-analysis obstructive sleep apnea

Author Community:

  • [ 1 ] [Cao, Yuan] Xi An Jiao Tong Univ, Coll Med, Affiliated Hosp 2, Dept Pulm & Crit Care Med, Xian, Shaanxi, Peoples R China
  • [ 2 ] [Wu, Shuang; Cao, Sancheng; Li, Qiao] Xi An Jiao Tong Univ, Affiliated Children Hosp, Clin Lab, 69 Xijuyuan Lane, Xian 710003, Shaanxi, Peoples R China
  • [ 3 ] [Zhang, Liyu; Yang, Ying; Li, Qiao] Xi An Jiao Tong Univ, Affiliated Children Hosp, Inst Pediat Dis, Xian, Shaanxi, Peoples R China

Reprint Author's Address:

  • Xi An Jiao Tong Univ, Affiliated Children Hosp, Clin Lab, 69 Xijuyuan Lane, Xian 710003, Shaanxi, Peoples R China.

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Source :

MEDICINE

ISSN: 0025-7974

Year: 2018

Issue: 51

Volume: 97

1 . 8 7

JCR@2018

1 . 8 8 9

JCR@2020

ESI Discipline: CLINICAL MEDICINE;

ESI HC Threshold:114

JCR Journal Grade:2

CAS Journal Grade:3

Cited Count:

WoS CC Cited Count: 28

SCOPUS Cited Count: 56

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 11

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