Self-powered　photodetectors　(PDs)　have　long　been　realized　by　utilizing　photovoltaic　effect　and　their　performances　can　be　effectively　enhanced　by　introducing　the　piezo-phototronic　effect.　Recently,　a　novel　pyro-phototronic　effect　is　invented　as　an　alternative　approach　for　performance　enhancement　of　self-powered　PDs.　Here,　a　self-powered　organic/inorganic　PD　is　demonstrated　and　the　influences　of　externally　applied　strain　on　the　pyro-phototronic　and　the　photovoltaic　effects　are　thoroughly　investigated.　Under　325　nm　2.30　mW　cm(-2)　UV　illumination　and　at　a　-0.45%　compressive　strain,　the　PD＇s　photocurrent　is　dramatically　enhanced　from　approximate　to　14.5　to　approximate　to　103　nA　by　combining　the　pyro-phototronic　and　piezo-phototronic　effects　together,　showing　a　significant　improvement　of　over　600%.　Theoretical　simulations　have　been　carried　out　via　the　finite　element　method　to　propose　the　underlying　working　mechanism.　Moreover,　the　pyro-phototronic　effect　can　be　introduced　by　applying　a　-0.45%　compressive　strain　to　greatly　enhance　the　PD＇s　response　to　442　nm　illumination,　including　photocurrent,　rise　time,　and　fall　time.　This　work　provides　in-depth　understandings　about　the　pyro-phototronic　and　the　piezo-phototronic　effects　on　the　performances　of　self-powered　PD　to　light　sources　with　different　wavelengths　and　indicates　huge　potential　of　these　two　effects　in　optoelectronic　devices.