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Abstract:
本发明公开了HP-β-CD-GMA-PEI作为口服和经肺吸收促进剂的应用。HP-β-CD-GMA-PEI作为吸收促进剂,能明显促进水溶性大分子难吸收药物口服和经肺吸收;同时,毒性考察结果显示HP-β-CD-GMA-PEI对口服和肺部吸收部位黏膜无明显损伤,因此HP-β-CD-GMA-PEI是安全的吸收促进剂,可应用于大分子药物口服和经肺吸收制剂中,用于改善水溶性大分子难吸收药物,尤其是蛋白肽类药物口服和经肺吸收的生物利用度。
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Patent Info :
Type: 发明专利
Patent No.: CN201310303102.6
Filing Date: 2013-07-18
Publication Date: 2013-11-27
Pub. No.: CN103405777A
Applicants: 西安交通大学
Legal Status: 有权
Cited Count:
WoS CC Cited Count: 0
SCOPUS Cited Count:
ESI Highly Cited Papers on the List: 0 Unfold All
WanFang Cited Count:
Chinese Cited Count:
30 Days PV: 2
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