Query：
学者姓名：王岗
Refining：
Year
Type
Indexed by
Source
Complex
Co-Author
Language
Clean All
Abstract ：
目的 探讨重症监护室(ICU)成年急性呼吸衰竭(acute respiratory failure,ARF)患者入ICU 24 h内静脉血糖水平及血糖变异度对患者医院病死率的影响.方法 采用回顾性队列研究,纳入ICU多参数智能监护数据库Ⅱ(multiparameter intelligent monitoring in intensive careⅡ,MIMIC-Ⅱ)中单次入ICU且患有ARF,同时入住ICU后初始24 h内有多次静脉血糖监测记录的患者.提取患者的年龄、性别、种族、首次序贯器官衰竭评分、使用注射用胰岛素及患病情况(糖尿病、心力衰竭、肾衰竭及感染).将入ICU 24 h内静脉血糖均值及血糖变异系数分别用来评估血糖水平及变异度,使用单因素及多因素Logistic回归分析评估血糖水平及血糖变异度与患者医院病死率之间的关系.并在血糖水平及血糖变异度与是否患糖尿病间分别进行交互作用分析.结果 本研究共纳入1625例患者.从24 h内平均静脉血糖指标分析,低、中、高血糖水平患者的医院病死率分别为31.6％(171例)、35.4％(192例)及43.7％(237例),高血糖水平患者的医院病死率是低血糖水平患者的1.594倍(OR=1.594,95％CI 1.206～2.105);从24 h内血糖变异系数分析,低、中、高血糖变异患者的医院病死率分别为30.7％(166例)、38.0％(206例)及42.1％(228例),高血糖变异患者的医院病死率是低血糖变异患者的1.362倍(OR=1.362,95％CI 1.035～1.792).血糖水平(Pinteraction=0.178)及血糖变异度(Pinteraction=0.119)对医院病死率的影响在糖尿病患者与非糖尿病患者两组间比较差异无统计学意义(P<0.05).结论 ARF患者入ICU 24 h内高血糖水平及高血糖变异度是其医院病死率的危险因素.
Keyword ：
急性呼吸衰竭(ARF) 血糖变异度 血糖水平 医院病死率 重症监护室(ICU)
Cite：
Copy from the list or Export to your reference management。
| GB/T 7714 | 李佳媚 , 高雅 , 张静静 et al. 血糖水平及血糖变异度对ICU成年急性呼吸衰竭患者预后的影响 [J]. | 中国急救医学 , 2021 , 41 (3) : 196-200 . |
| MLA | 李佳媚 et al. "血糖水平及血糖变异度对ICU成年急性呼吸衰竭患者预后的影响" . | 中国急救医学 41 . 3 (2021) : 196-200 . |
| APA | 李佳媚 , 高雅 , 张静静 , 李若寒 , 金旭婷 , 张小玲 et al. 血糖水平及血糖变异度对ICU成年急性呼吸衰竭患者预后的影响 . | 中国急救医学 , 2021 , 41 (3) , 196-200 . |
| Export to | NoteExpress RIS BibTex |
Abstract ：
目的 探讨危重症患者入重症监护室(intensive care unit,ICU)时红细胞分布宽度(red cell distribution width,RDW)与病死率的相关性.方法 采用回顾性队列研究,纳入美国重症监护数据库Ⅱ 版本2.6(Multiparameter Intelligent Monitoring in Intensive CareⅡversion 2.6,MIMIC-Ⅱv2.6)中单次入院且ICU住院时长>24 h,同时有RDW检测记录的成年患者.根据RDW预测病死率的最佳cut-off值(14.55％)将研究对象分为低RDW组(RDW<14.55％)及高RDW组(RDW≥14.55％),比较两组的病死率,进一步使用单因素及多因素Logistic回归和Cox回归分析评估RDW与病死率的关系.结果 本研究最终共有13822例患者入组.高RDW组的医院病死率、ICU病死率、28 d病死率及1年病死率均高于低RDW组(分别为19.73％vs.8.42％,15.04％vs.6.65％,22.68％vs.9.12％,36.22％vs.14.45％,均P<0.001).RDW作为连续变量,多因素分析结果 显示,RDW越高,医院病死率(OR=1.227,95％CI 1.190～1.265)、ICU病死率(OR=1.180,95％CI 1.141～1.220)、28 d病死率(HR=1.161,95％CI 1.138～1.185)和1年病死率(HR=1.177,95％CI 1.159～1.195)越高.分组后回归分析结果 显示,与低水平RDW组相比,高水平RDW组患者的医院病死率增加0.912倍(OR=1.912,95％CI 1.683～2.172),ICU病死率增加0.673倍(OR=1.673,95％CI 1.452～1.928),28 d病死率增加0.850倍(HR=1.850,95％CI 1.675～2.043),1年病死率增加1.045倍(HR=2.045,95％CI 1.891～2.212),且存在统计学意义(P<0.001).结论 入ICU首次RDW增高是危重症患者死亡的危险因素.
Keyword ：
病死率 红细胞分布宽度(RDW) 重症监护室(ICU)
Cite：
Copy from the list or Export to your reference management。
| GB/T 7714 | 侯彦丽 , 金旭婷 , 李佳媚 et al. 红细胞分布宽度与危重症患者病死率的相关性研究 [J]. | 中国急救医学 , 2021 , 41 (2) : 111-116 . |
| MLA | 侯彦丽 et al. "红细胞分布宽度与危重症患者病死率的相关性研究" . | 中国急救医学 41 . 2 (2021) : 111-116 . |
| APA | 侯彦丽 , 金旭婷 , 李佳媚 , 张静静 , 骆艳妮 , 王小闯 et al. 红细胞分布宽度与危重症患者病死率的相关性研究 . | 中国急救医学 , 2021 , 41 (2) , 111-116 . |
| Export to | NoteExpress RIS BibTex |
Abstract ：
目的 探讨患者△D-二聚体升高与肺栓塞(PE)的相关性.方法 采用回顾性病例对照研究,共纳入我院2017年6月～2018年7月行肺动脉血管造影检查(CTPA)的260例患者为研究对象,纳入患者均行CTPA,并且在CT-PA前1周内行两次D-二聚体监测(两次间隔时间＞1 d).根据△D-二聚体结果分为△D-二聚体＞0组与△D-二聚体≤0组.采用单因素及多因素Logistic回归模型分析△D-二聚体升高对PE发生的可能性.结果 本研究共收集△D-二聚体＞0组150例与△D-二聚体≤0组110例;△D-二聚体在肺栓塞组的中位数为2960,在非肺栓塞组为5,差异有统计学意义(P＜0.001);△D-二聚体＞0组在PE中占41.3％,△D-二聚体≤0组在PE中占20.0％,差异有统计学意义(P＜0.001).单因素Logistic回归分析显示:△D-二聚体＞0发生PE的可能性是△D-二聚体≤0的2.755倍;多因素Logistic回归分析显示:△D-二聚体＞0组发生PE的可能性是△D-二聚体≤0组的2.829倍.在非肿瘤患者中,△D-二聚体＞0发生PE的可能性是△D-二聚体≤0的3.038倍;多因素Logistic回归显示:△D-二聚体＞0组发生PE的风险是△D-二聚体≤0组的2.870倍,差异亦有统计学意义(P＜0.05).结论 △D-二聚体＞0与PE之间有较高的相关性,关注D-二聚体变化可提高PE的早期诊断率,尤其在非肿瘤患者中更显著.
Keyword ：
D-二聚体 肺动脉血管造影 肺栓塞 相关性
Cite：
Copy from the list or Export to your reference management。
| GB/T 7714 | 骆艳妮 , 王岗 , 王小闯 et al. △D-二聚体与肺栓塞发生事件的相关性 [J]. | 西部医学 , 2021 , 33 (4) : 517-520 . |
| MLA | 骆艳妮 et al. "△D-二聚体与肺栓塞发生事件的相关性" . | 西部医学 33 . 4 (2021) : 517-520 . |
| APA | 骆艳妮 , 王岗 , 王小闯 , 李佳媚 , 张静静 , 侯彦丽 . △D-二聚体与肺栓塞发生事件的相关性 . | 西部医学 , 2021 , 33 (4) , 517-520 . |
| Export to | NoteExpress RIS BibTex |
Abstract ：
To assess the association between serum ammonia level upon admission during the initial intensive care unit (ICU) stay and mortality.This retrospective cohort study included 2703 adult patients in eICU Collaborative Research Database. The ICU mortality within ammonia deciles were assessed. Logistic regression analyses were performed to analyze the relationship between ammonia and mortality.We defined three ammonia categories: <47, 47-111, and ≥111 μg/dL, corresponding to low, intermediate, and high ICU mortality. Increased ammonia was significantly associated with increased ICU mortality (per 10 μg/dL increase: odds ratio, 1.070 [95% confidence intervals, 1.05-1.09]; intermediate vs. low: 1.90 [1.41-2.56]; high vs. low: 4.38 [2.99-6.41]) and in-hospital mortality (1.06 [1.04-1.08]; 1.45 [1.13-1.87]; 3.41 [2.43-4.79]). Adding ammonia to the Acute Physiology and Chronic Health Evaluation (APACHE) IV score improved the area under the curve from 0.826 to 0.839 (P < 0.001) and from 0.806 to 0.813 (P = 0.001) for ICU and in-hospital mortality, respectively. Interaction and subgroup analyses demonstrated consistent results in patients with different APACHE IV scores, with or without hepatic diseases.Elevated serum ammonia level in critically ill patients upon admission was an early risk factor for higher ICU and in-hospital mortality.
Keyword ：
Ammonia eICU collaborative research database Intensive care unit Mortality
Cite：
Copy from the list or Export to your reference management。
| GB/T 7714 | Li Jiamei , Li Ruohan , Gao Ya et al. Increasing serum ammonia level is a risk factor for the prognosis of critically ill patients: A multicenter retrospective cohort study. [J]. | Journal of critical care , 2021 , 62 : 218-222 . |
| MLA | Li Jiamei et al. "Increasing serum ammonia level is a risk factor for the prognosis of critically ill patients: A multicenter retrospective cohort study." . | Journal of critical care 62 (2021) : 218-222 . |
| APA | Li Jiamei , Li Ruohan , Gao Ya , Jin Xuting , Zhang Jingjing , Ren Jiajia et al. Increasing serum ammonia level is a risk factor for the prognosis of critically ill patients: A multicenter retrospective cohort study. . | Journal of critical care , 2021 , 62 , 218-222 . |
| Export to | NoteExpress RIS BibTex |
Abstract ：
The coronavirus disease 2019 (COVID-19) is presently the most pressing public health concern worldwide. Cytokine storm is an important factor leading to death of patients with COVID-19. This study aims to characterize serum cytokines of patients with severe or critical COVID-19. Clinical records were obtained from 149 patients who were tested at the Sino-French New City Branch of Tongji Hospital from 30 January to 30 March 2020. Data regarding the clinical features of the patients was collected and analyzed. Among the 149, 45 (30.2%) of them had severe conditions and 104 (69.8%) of that presented critical symptoms. In the meantime, 80 (53.7%) of that 149 died during hospitalization. Of all, male patients accounted for 94 (69.1%). Compared with patients in severe COVID-19, those who in critical COVID-19 had significantly higher levels of tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), IL-8, and IL-10. Moreover, the passed-away patients had considerably higher levels of TNF-alpha, IL-6, IL-8, and IL-10 than those survived from it. Regression analysis revealed that serum TNF-alpha level was an independent risk factor for the death of patient with severe conditions. Among the proinflammatory cytokines (IL-1 beta, TNF-alpha, IL-8, and IL-6) analyzed herein, TNF-alpha was seen as a risk factor for the death of patients with severe or critical COVID-19. This study suggests that anti-TNF-alpha treatment allows patients with severe or critical COVID-19 pneumonia to recover.
Keyword ：
COVID-19 cytokine storm illness severity mortality TNF-alpha
Cite：
Copy from the list or Export to your reference management。
| GB/T 7714 | Jia, Fang , Wang, Gang , Xu, Jing et al. Role of tumor necrosis factor-a in the mortality of hospitalized patients with severe and critical COVID-19 pneumonia [J]. | AGING-US , 2021 , 13 (21) : 23895-23912 . |
| MLA | Jia, Fang et al. "Role of tumor necrosis factor-a in the mortality of hospitalized patients with severe and critical COVID-19 pneumonia" . | AGING-US 13 . 21 (2021) : 23895-23912 . |
| APA | Jia, Fang , Wang, Gang , Xu, Jing , Long, Junhong , Deng, Fuxue , Jiang, Wei . Role of tumor necrosis factor-a in the mortality of hospitalized patients with severe and critical COVID-19 pneumonia . | AGING-US , 2021 , 13 (21) , 23895-23912 . |
| Export to | NoteExpress RIS BibTex |
Abstract ：
Background: The inflammatory reaction is the main cause of acute respiratory distress syndrome and multiple organ failure in patients with Coronavirus disease 2019, especially those with severe and critical illness. Several studies suggested that high-dose vitamin C reduced inflammatory reaction associated with sepsis and acute respiratory distress syndrome. This study aimed to determine the efficacy and safety of high-dose vitamin C in Coronavirus disease 2019. Methods: We included 76 patients with Coronavirus disease 2019, classified into the high-dose vitamin C group (loading dose of 6g intravenous infusion per 12 hr on the first day, and 6g once for the following 4 days, n=46) and the standard therapy group (standard therapy alone, n=30). Results: The risk of 28-day mortality was reduced for the high-dose vitamin C versus the standard therapy group (HR=0.14, 95% CI, 0.03-0.72). Oxygen support status was improved more with high-dose vitamin C than standard therapy (63.9% vs 36.1%). No safety events were associated with high-dose vitamin C therapy. Conclusion: High-dose vitamin C may reduce the mortality and improve oxygen support status in patients with Coronavirus disease 2019 without adverse events.
Keyword ：
ascorbic acid coronavirus disease 2019 COVID-19 mortality safety
Cite：
Copy from the list or Export to your reference management。
| GB/T 7714 | Gao, Dengfeng , Xu, Min , Wang, Gang et al. The efficiency and safety of high-dose vitamin C in patients with COVID-19: a retrospective cohort study [J]. | AGING-US , 2021 , 13 (5) : 7020-7034 . |
| MLA | Gao, Dengfeng et al. "The efficiency and safety of high-dose vitamin C in patients with COVID-19: a retrospective cohort study" . | AGING-US 13 . 5 (2021) : 7020-7034 . |
| APA | Gao, Dengfeng , Xu, Min , Wang, Gang , Lv, Jianrui , Ma, Xiaorong , Guo, Yonghong et al. The efficiency and safety of high-dose vitamin C in patients with COVID-19: a retrospective cohort study . | AGING-US , 2021 , 13 (5) , 7020-7034 . |
| Export to | NoteExpress RIS BibTex |
Abstract ：
Background Previous studies have suggested that sleep timing is associated with cardiovascular risk factors. However, there is no evidence on the relationship between sleep timing and congestive heart failure (CHF). We aimed to examine this relationship in this study. Methods and Results We recruited 4765 participants (2207 men; mean age, 63.6 +/- 11.0 years) from the SHHS (Sleep Heart Health Study) database in this multicenter prospective cohort study. Follow-up was conducted until the first CHF diagnosis between baseline and the final censoring date. Sleep timing (bedtimes and wake-up times on weekdays and weekends) was based on a self-reported questionnaire. Cox proportional hazard models were constructed to investigate the association between sleep timing and CHF. During the mean follow-up period of 11 years, 519 cases of CHF (10.9%) were reported. The multivariable Cox proportional hazards models revealed that participants with weekday bedtimes >12:00 am (hazard ratio [HR], 1.56; 95% CI, 1.15-2.11; P=0.004) and from 11:01 pm to 12:00 am (HR, 1.25; 95% CI, 1.00-1.56; P=0.047) had an increased risk of CHF compared with those with bedtimes from 10:01 pm to 11:00 pm. After stratified analysis, the association was intensified in participants with a self-reported sleep duration of 6 to 8 hours. Furthermore, wake-up times >8:00 am on weekdays (HR, 1.53; 95% CI, 1.07-2.17; P=0.018) were associated with a higher risk of incident CHF than wake-up times <= 6:00 am. Conclusions Delayed bedtimes (>11:00 pm) and wake-up times (>8:00 am) on weekdays were associated with an increased risk of CHF.
Keyword ：
bedtime congestive heart failure sleep timing up time wake‐
Cite：
Copy from the list or Export to your reference management。
| GB/T 7714 | Yan, Bin , Li, Ruohan , Li, Jiamei et al. Sleep Timing May Predict Congestive Heart Failure: A Community-Based Cohort Study [J]. | JOURNAL OF THE AMERICAN HEART ASSOCIATION , 2021 , 10 (6) . |
| MLA | Yan, Bin et al. "Sleep Timing May Predict Congestive Heart Failure: A Community-Based Cohort Study" . | JOURNAL OF THE AMERICAN HEART ASSOCIATION 10 . 6 (2021) . |
| APA | Yan, Bin , Li, Ruohan , Li, Jiamei , Jin, Xuting , Gao, Fan , Gao, Ya et al. Sleep Timing May Predict Congestive Heart Failure: A Community-Based Cohort Study . | JOURNAL OF THE AMERICAN HEART ASSOCIATION , 2021 , 10 (6) . |
| Export to | NoteExpress RIS BibTex |
Abstract ：
Evidence indicates that glucose variation (GV) plays an important role in mortality of critically ill patients. We aimed to investigate the relationship between the coefficient of variation of 24-h venous blood glucose (24-hVBGCV) and mortality among patients with acute respiratory failure. The records of 1625 patients in the Multiparameter Intelligent Monitoring in Intensive Care II (MIMIC II) database were extracted. The 24-hVBGCV was calculated as the ratio of the standard deviation (SD) to the mean venous blood glucose level, expressed as a percentage. The outcomes included ICU mortality and in-hospital mortality. Participants were divided into three subgroups based on tertiles of 24-hVBGCV. Multivariable logistic regression models were used to evaluate the relationship between 24-hVBGCV and mortality. Sensitivity analyses were also performed in groups of patients with and without diabetes mellitus. Taking the lowest tertile as a reference, after adjustment for all the covariates, the highest tertile was significantly associated with ICU mortality [odds ratio (OR), 1.353; 95% confidence interval (CI), 1.018-1.797] and in-hospital mortality (OR, 1.319; 95% CI, 1.003-1.735), especially in the population without diabetes. The 24-hVBGCV may be associated with ICU and in-hospital mortality in patients with acute respiratory failure in the ICU, especially in those without diabetes.
Cite：
Copy from the list or Export to your reference management。
| GB/T 7714 | Zhang, Xiaoling , Zhang, Jingjing , Li, Jiamei et al. Relationship between 24-h venous blood glucose variation and mortality among patients with acute respiratory failure [J]. | SCIENTIFIC REPORTS , 2021 , 11 (1) . |
| MLA | Zhang, Xiaoling et al. "Relationship between 24-h venous blood glucose variation and mortality among patients with acute respiratory failure" . | SCIENTIFIC REPORTS 11 . 1 (2021) . |
| APA | Zhang, Xiaoling , Zhang, Jingjing , Li, Jiamei , Gao, Ya , Li, Ruohan , Jin, Xuting et al. Relationship between 24-h venous blood glucose variation and mortality among patients with acute respiratory failure . | SCIENTIFIC REPORTS , 2021 , 11 (1) . |
| Export to | NoteExpress RIS BibTex |
Abstract ：
Background: Upper respiratory infections (URIs) are among the most common diseases. However, the related burden has not been comprehensively evaluated. Thus, we designed the present study to describe the global and regional burden of URIs from 1990 to 2019. Methods: A secondary analysis was performed on the incidence, mortality, and disability-adjusted life years (DALYs) of URIs in different sex and age groups, from 21 geographic regions, 204 countries and territories, between 1990 and 2019, using the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019. Countries and territories were categorized according to Socio-demographic Index (SDI) quintiles. Findings: Globally, the incident cases of URIs reached 17.2 (95% uncertainty interval: 15.4 to 19.3) billion in 2019, which accounted for 42.83% (40.01% to 45.77%) cases from all causes in the GBD 2019 study. The age-standardized incidence rate remained stable from 1990 to 2019, while significant decreases were found in the mortality and DALY rate. The highest age-standardized incidence rates from 1990 to 2019 and the highest age-standardized DALY rates after 2011 were observed in high SDI regions. Among all the age groups, children under five years old suffered from the highest incidence and DALY rates, both of which were decreased with increasing age. Fatal con-sequences of URIs occurred mostly in the elderly and children under five years old. Interpretation: The present study provided comprehensive estimates of URIs burden for the first time. Our find-ings, highlighting the substantial incidence and considerable DALYs due to URIs, are expected to attract more attention to URIs and provide future explorations in the prevention and treatment with epidemiological evidence. Funding: The study was funded by the National Natural Science Foundation of China (81770057). (c) 2021 The Author(s). Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
Keyword ：
Epidemiology Global burden of disease Incidence Mortality Respiratory tract infections
Cite：
Copy from the list or Export to your reference management。
| GB/T 7714 | Jin, Xuting , Ren, Jiajia , Li, Ruohan et al. Global burden of upper respiratory infections in 204 countries and territories, from 1990 to 2019 [J]. | ECLINICALMEDICINE , 2021 , 37 . |
| MLA | Jin, Xuting et al. "Global burden of upper respiratory infections in 204 countries and territories, from 1990 to 2019" . | ECLINICALMEDICINE 37 (2021) . |
| APA | Jin, Xuting , Ren, Jiajia , Li, Ruohan , Gao, Ya , Zhang, Haoying , Li, Jiamei et al. Global burden of upper respiratory infections in 204 countries and territories, from 1990 to 2019 . | ECLINICALMEDICINE , 2021 , 37 . |
| Export to | NoteExpress RIS BibTex |
Cite：
Copy from the list or Export to your reference management。
| GB/T 7714 | Yu, Yue-Tian , Liu, Jiao , Hu, Bo et al. Expert consensus on the use of human serum albumin in critically ill patients [J]. | CHINESE MEDICAL JOURNAL , 2021 , 134 (14) : 1639-1654 . |
| MLA | Yu, Yue-Tian et al. "Expert consensus on the use of human serum albumin in critically ill patients" . | CHINESE MEDICAL JOURNAL 134 . 14 (2021) : 1639-1654 . |
| APA | Yu, Yue-Tian , Liu, Jiao , Hu, Bo , Wang, Rui-Lan , Yang, Xiang-Hong , Shang, Xiu-Ling et al. Expert consensus on the use of human serum albumin in critically ill patients . | CHINESE MEDICAL JOURNAL , 2021 , 134 (14) , 1639-1654 . |
| Export to | NoteExpress RIS BibTex |
Export
| Results： |
Selected to |
| Format： |
