For　three-dimensional　cell　spreading,　a　tube　type　scaffolds　constructed　by　porous　rolling　plane　is　designed,　and　cells　seeded　on　the　surface　are　bent　as　a　spiral.　The　channels　in　the　scaffold　promote　culture　medium　permeating　and　material　interchange.　A　bionic　structure　designed　for　this　kind　of　scaffold　is　beneficial　to　measure　the　shape　of　liver　vessels　from　liver　vascular　casting　and　extract　the　bionics　parameters　by　statistic　analysis,　which　has　different　hierarchies　as　a　tree　to　imitate　the　functions　of　artery　and　vein.　The　micro-pores　of　the　scaffold　material　also　imitated　capillary.　With　the　changed　parameters,　finite-element　models　are　established　to　compare　the　flow　field　distribution　of　different　channel　shapes　on　scaffolds.　The　results　verify　the　most　uniform　flow　field　and　the　highest　nutrition　transfer　efficiency,　which　enlarges　the　effective　area　of　medium　spread　in　scaffold,　and　provides　better　micro-environment　for　cells　survival,　multiplication　and　migrate.