Purpose　Owing　to　acoustic-pressure　dependence,　amplitudes　of　backscattered-echoes　of　encapsulated　microbubbles　(MBs)　are　unavoidably　regulated　by　an　uneven　acoustic　field,　resulting　in　the　misestimation　of　hemodynamics　in　conventional　amplitude-coding　dynamic　contrast-enhanced　ultrasound　(DCEUS)　with　focused　pulse　transmission.　This　study　aimed　to　investigate　the　feasibility　and　performance　of　Nakagami　statistical-feature　parametric　imaging　to　recover　the　above　misestimation.　Methods　Logarithmic　Nakagami　parameter　(m)-coding　DCEUS　scheme　was　investigated　via　simulation　and　in　vitro　MB　phantoms　as　well　as　in　vivo　kidney-perfusion　experiments　of　four　rabbits　in　the　uneven　acoustic　fields　with　two　different　focal　depths.　In　vivo　tissue　artifacts　for　m　estimation　were　suppressed　by　pulse-inversion　second-harmonic　imaging　and　its　robustness　was　enhanced　by　multiscale　moment-estimation　strategy.　Time-Nakagami-m　curves　and　the　corresponding　perfusion　metrics　of　intensity　and　volume　were　calculated　from　the　logarithmic　m-coding　DCEUS　images　within　the　prefocal　and　focal　regions.　These　curves　and　metrics　were　further　compared　with　the　perfusion　curves　and　metrics　estimated　from　the　conventional　amplitude-coding　images　within　the　same　regions.　Results　Compared　with　amplitudes　of　nonlinear　scattering　MB　echoes,　their　logarithmic　m　values　were　relatively　independent　of　the　changes　in　acoustics　pressures.　Compared　with　the　fixed-scale　moment-estimation,　the　perfusion　intensity　estimated　from　logarithmic　m-coding　DCEUS　scheme　using　multiscale　statistical　moment-estimation　had　smaller　differences　between　the　prefocal　and　focal　regions.　The　differences　of　perfusion　intensity　induced　by　an　uneven　acoustic　field　decreased　to　3.47%　+/-　1.58　%.　The　differences　decreased　by　the　logarithmic　m-coding　DCEUS　scheme　were　further　regulated　by　threshold　values　of　m　estimation.　Conclusions　The　logarithmic　m-coding　DCEUS　scheme　could　recover　the　underestimated　MB　backscattered-echoes　and　the　misestimated　perfusion　intensity　induced　by　the　uneven　acoustic　field.　The　scheme　had　the　potential　to　weaken　the　limitation　of　microvasculature　identification　and　hemodynamic　characterization　marked　by　MBs　within　tissues　or　tumors　in　the　uneven　acoustic　field.