Recipients　of　influenza　A　(HI　NI)　vaccine　in　1976　had　an　increased　risk　for　the　neurologic　disorder　Guillain-Barre　syndrome　(GBS).　Anti-ganglioside　antibodies,　which　might　be　associated　with　the　development　of　CBS,　were　previously　reported　to　be　induced　in　mice　immunized　with　an　H1N1　vaccine　of　1976　or　another　influenza　vaccine.　In　this　study　we　analyzed　anti-ganglioside　antibodies　in　human　subjects　infected　with　or　vaccinated　against　2009　pandemic　H1N1,　including　eight　patients　diagnosed　to　have　post-vaccination　CBS.　Antibodies　against　GM1　or　another　ganglioside　were　not　detected　in　any　subject　or　in　vaccinated　mice.　Our　results　did　not　support　the　induction　of　anti-ganglioside　antibodies　by　influenza　viruses　or　vaccines.　(C)　2012　Elsevier　Ltd.　All　rights　reserved.