Advanced　titanium　(Ti)　based　bone　implants　with　antibacterial　and　osteogenic　activities　are　extremely　needed　in　clinics.　Herein,　biomimetic　hierarchical　micropore/nanorod　patterned　coatings　(MNRs)　on　Ti　were　developed,　in　which　the　nanorods　revealed　a　fixed　interrod　spacing　of　about　70　nm　and　consisted　of　fluorine　(F)　incorporated　Ca9Sr1(PO4)(6)(OH)(2)　(Sr-1-　HA,　strontium　containing　hydroxyapatite)　with　the　fixed　Sr　but　different　F　content.　The　incorporation　of　F　was　determined　by　XRD,　FTTR,　and　TEM,　revealing　the　substitution　of　OH-　in　Sr-1　-HA　to　F-.　The　topography,　surface　roughness,　and　hydrophilic　nature　of　MNRs　were　not　apparently　affected　by　the　incorporation　of　F.　The　antibacterial　and　osteogenic　activities　of　MNRs　were　assessed　in　vitro　and　in　a　bacterial-infected　rabbit　model.　Both　the　in　vitro　and　in　vivo　results　showed　that　F-free　and　similar　to　1　wt　%　F　doped　MNR　significantly　promoted　osteogenic　activity　compared　to　that　of　Ti　but　showed　a　lack　of　antibacterial　activity.　The　incorporation　of　a　higher　dose　of　F　led　to　the　significantly　improved　antibacterial　and　osteogenic　activities,　and　the　effects　were　related　to　the　incorporated　F　dose.　In　total,　compared　to　F-free,　similar　to　1,　similar　to　2,　and　similar　to　7　wt　%　F　doped　MNRs,　%　F　doped　MNR　significantly　enhanced　antibacterial　and　osteogenic　activities,　especially　new　bone　formation　and　osseointegration　in　the　bacteria　infected　case,　showing　a　high　potential　as　the　next　generation　of　advanced　bone　implant.