Allelic　frequencies　and　genetic　polymorphisms　of　19　short　tandem　repeats　loci　were　investigated　so　as　to　provide　more　genetic　data　for　forensic　applications　in　Chinese　Uzbek　group;　besides,　we　evaluated　phylogenetic　relationships　of　Uzbek　group　with　other　populations.　All　loci　were　observed　to　conform　to　Hardy-Weinberg　equilibrium　after　Bonferroni＇s　correction.　Two　hundred　and　nine　alleles　were　identified　in　212　unrelated　healthy　Uzbek　individuals　and　their　allelic　frequencies　ranged　from　0.0024　to　0.5259.　The　cumulative　discrimination　power　and　cumulative　probability　of　exclusion　were　0.999999999999999999999996501　and　0.999999998759,　respectively.　The　results　of　population　differentiation　comparison,　principal　component　analysis,　and　phylogenetic　tree　revealed　that　Uzbek　group　had　close　relationships　with　Uyghur　and　Kazakh　groups.