Nano　rotor　is　of　great　value　in　military　and　civilian　applications.　Due　to　its　nano　size,　it　works　at　an　ultra-low　Reynolds　number　and　aerodynamic　performance　deteriorates　dramatically.　The　bio-inspired　nano　rotor　is　carried　out　to　improve　the　rotor　propulsive　performance.　Unsteady　vortex　lattice　method　(UVLM)　model　is　established　fully　considering　the　influence　of　induced　drag　and　wake　vortex　distortion　on　aerodynamic　forces.　The　aim　is　to　quickly　and　accurately　simulate　the　flow　field　around　the　bio-inspired　nano　rotor　and　to　efficiently　perform　the　aerodynamic　calculation　to　optimise　the　design　of　the　bio-inspired　rotor.　The　rotor　parameters　and　motion　parameters　such　as　aspect　ratio,　taper　ratio　and　camber　are　studied　using　UVLM.　It　is　found　that　the　aerodynamic　performance　of　the　rotor　increased　with　the　aspect　ratio.　The　quality　factor　changes　parabolically　with　the　taper　ratio　and　camber,　and　there　is　an　optimal　value　for　the　ratio　and　camber,　respectively.　The　influences　of　pitching　angle　and　frequency　are　investigated　as　well.　Results　show　that　the　bio-inspired　motion　improves　the　propulsion　performance　of　nano　rotor.　©　2020　Institution　of　Engineering　and　Technology.　All　rights　reserved.