Advanced　biogas　power　generation　technology　has　been　attracting　attentions,　which　contributes　to　the　waste　disposal　and　the　mitigation　of　greenhouse　gas　emissions.　This　work　proposes　and　models　a　novel　biogas-fed　hybrid　power　generation　system　consisting　of　solid　oxide　fuel　cell,　water　gas　shift　reaction,　thermal　swing　adsorption　and　proton　exchange　membrane　fuel　cell　(SOFC-WGS-TSA-PEMFC).　The　thermodynamic,　exergetic,　and　thermo-economic　analyses　of　this　hybrid　system　for　power　generation　were　conducted　to　comprehensively　evaluate　its　performance.　It　was　found　that　the　novel　biogas-fed　hybrid　system　has　a　gross　energy　conversion　efficiency　of　68.63%　and　exergy　efficiency　of　65.36%,　indicating　high　efficiency　for　this　kind　of　hybrid　power　technology.　The　market　sensitivity　analysis　showed　that　the　hybrid　system　also　has　a　low　sensitivity　to　market　price　fluctuation.　Under　the　current　subsidy　level　for　the　distributed　biogas　power　plant,　the　levelized　cost　of　energy　can　be　lowered　to　0.02942　$/kWh　for　a　1　MW　scale　system.　Accordingly,　the　payback　period　and　annual　return　on　investment　can　reach　1.4　year　and　about　20%,　respectively.　These　results　reveal　that　the　proposed　hybrid　system　is　promising　and　economically　feasible　as　a　distributed　power　plant,　especially　for　the　small　power　scale　(no　more　than　2　MW).　©　2020　Hydrogen　Energy　Publications　LLC