Preformed　crowns　are　preferred　to　reduce　the　failure　risk　of　restoration　of　primary　teeth,　but　some　drawback　of　conventional　material　is　still　a　main　barrier　for　their　clinical　use.　Polyether　etherketone　(PEEK),　a　tooth　colored,　high-performance　thermoplastic　polymer,　has　been　recognized　as　a　promising　alternative　to　manufacture　the　restoration　of　primary　teeth.　However,　the　hydrophobic　surface　and　low　surface　energy　of　PEEK　make　it　hard　to　establish　a　strong　and　durable　adhesion.　In　this　study,　we　have　evaluated　a　modification　method　of　polydopamine　(PDA)　coating　with　plasma　pretreatment　for　the　PEEK　films　by　physical　and　chemical　characterization,　bonding　properties,　and　biocompatibility.　The　surface　properties　of　PEEK　were　well-characterized　by　scanning　electron　microscope　(SEM)　and　X-ray　photoelectron　spectroscopy　(XPS).　The　adhesive　strength　of　the　PEEK　films　was　greatly　improved　without　significant　reduction　of　the　proliferation　rate　of　human　gingival　fibroblast　cells　in　MTT　and　Live/Dead　assays.　Therefore,　PDA　coating　with　plasma　pretreatment　may　give　a　new　solution　for　effective　clinical　application　of　PEEK　in　primary　performed　crowns.