Nanolayered　materials　exhibit　unique　plastic　deformation　behavior,　i.e.,　a　bulk-like　to　small-scale　plasticity　transition　and　a　scaling　behavior　of　extremely　small　activation　volume　(V-not　asymptotic　to　＜　10b(3))　with　intrinsic　size.　This　unusual　plastic　transition　phenomenon　likely　stems　from　the　dislocations　respectively　emit　from　interfaces　and　Frank-Read-type　bulk　sources　below　and　above　a　critical　intrinsic　size　similar　to　20　nm.　We　quantitatively　capture　the　scaling　relationship　between　strain　rate　sensitivity　and　intrinsic　size　by　a　phenomenological　model　based　on　the　Orowan-Frank-Read　process.　(C)　2014　Elsevier　B.　V.　All　rights　reserved.