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Abstract:
Objective: To investigate the difference in stimulated submandibular/sublingual salivary protein between two children groups who came from two districts where the fluoride concentrations in drinking water were 3.68 mg·L-1 (F3.68 Group) and 1.00 mg·L-1 (F1.00 Group). Methods: We measured the flow rate, the concentration of total proteins and the protein volume secreted per min of stimulated parotid saliva, and analyzed the composition of salivary proteins and their compositional proportions. Results: 1 The flow rate of stimulated submandibular/sublingual saliva in F3.68 Group were higher than that in F1.00 Group (P<0.1). 2 The total protein concentration of stimulated submandibular/sublingual saliva in F3.68 Group was significantly lower than that in F1.00 Group (P<0.01). 3 The protein volume secreted per min by submandibular/sublingual saliva in F3.68 Group was markedly lower than that in F1.00 Group(P<0.05). 4 The submandibular/sublingual salivary protein patterns were different between the two groups. 10 to 12 protein bands were found. The incidence of B10, B12 in F3.68 Group was obviously lower than that in F1.00 Group (P<0.05). The proportion of B9 in total protein volume in F3.68 Group was remarkably higher than that in F1.00 Group (P<0.05). Conclusion: The stimulated parotid salivary protein of the two children groups was different in volume. It indicates that the excessive fluoride in drinking water can affect children's salivary protein expression.
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Journal of Xi'an Jiaotong University (Medical Sciences)
ISSN: 1671-8259
Year: 2003
Issue: 3
Volume: 24
Page: 224-246
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WoS CC Cited Count: 0
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ESI Highly Cited Papers on the List: 0 Unfold All
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30 Days PV: 2
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