Purpose:　This　study　aims　to　develop　a　multi-material　stereolithography　(MMSL)　technique　to　directly　fabricate　a　biphasic　osteochondral　scaffold.　Design/methodology/approach:　A　bespoke　prototype　MMSL　system　was　developed　based　on　a　bottom-up　mask　projection　approach.　The　system　was　controlled　by　a　multi-material　fabrication　algorithm　with　minimum　number　of　switching　cycles　during　fabrication.　A　variable-power　light　source　was　used　to　fabricate　materials　with　significantly　different　curing　characteristics.　The　light-curable　poly(ethylene　glycol)　diacrylate　(PEGDA)　hydrogel　and　beta-tricalcium　phosphate　(β-TCP)　ceramic　suspension　were　used　for　fabricating　the　biphasic　osteochondral　scaffold.　Findings:　The　bonding　strength　of　the　multi-material　interface　is　shown　to　be　mainly　affected　by　the　type　of　photopolymer,　rather　than　the　switching　of　the　materials　in　MMSL.　Lighting　power　densities　of　2.64　and　14.98　mW/cm2　were　used　for　curing　the　PEGDA　hydrogel　and　the　ß-TCP　ceramic　suspension,　respectively.　A　biphasic　osteochondral　scaffold　with　complex　interface　was　successfully　fabricated.　Originality/value:　This　study　proposes　a　potential　technical　method　(MMSL)　for　manufacturing　a　complex　biphasic　osteochondral　scaffold　composing　a　PEGDA　hydrogel/ß-TCP　ceramic　composite　in　a　time-efficient　and　precise　manner.　The　designed　bone-cartilage　scaffold　interface　and　the　surface　of　the　cartilage　scaffold　can　be　precisely　manufactured.　©　2018,　Emerald　Publishing　Limited.